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Protein

Homeobox-leucine zipper protein HAT2

Gene

HAT2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Probable transcription factor that plays a role in auxin-mediated morphogenesis. Negatively regulates lateral root elongation.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi127 – 186HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • DNA binding Source: TAIR
  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • auxin-activated signaling pathway Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • response to auxin Source: TAIR
  • shade avoidance Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
  • unidimensional cell growth Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein HAT2
Alternative name(s):
Homeodomain-leucine zipper protein HAT2
Short name:
HD-ZIP protein 2
Gene namesi
Name:HAT2
Ordered Locus Names:At5g47370
ORF Names:MQL5.23
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G47370.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000488991 – 283Homeobox-leucine zipper protein HAT2Add BLAST283

Proteomic databases

PaxDbiP46601.

PTM databases

iPTMnetiP46601.

Expressioni

Inductioni

By indole-3-acetic acid (IAA).1 Publication

Gene expression databases

GenevisibleiP46601. AT.

Interactioni

Subunit structurei

Interacts with RBR1.1 Publication

Protein-protein interaction databases

BioGridi20032. 10 interactors.
DIPiDIP-60613N.
IntActiP46601. 9 interactors.
STRINGi3702.AT5G47370.1.

Structurei

3D structure databases

ProteinModelPortaliP46601.
SMRiP46601.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni194 – 215Leucine-zipperAdd BLAST22

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000241612.
InParanoidiP46601.
KOiK09338.
OMAiVSINPWV.
OrthoDBiEOG09360N3V.
PhylomeDBiP46601.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR006712. HD-ZIP_N.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003106. Leu_zip_homeo.
[Graphical view]
PfamiPF02183. HALZ. 1 hit.
PF04618. HD-ZIP_N. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00340. HALZ. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46601-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMMGKEDLGL SLSLGFSQNH NPLQMNLNPN SSLSNNLQRL PWNQTFDPTS
60 70 80 90 100
DLRKIDVNSF PSTVNCEEDT GVSSPNSTIS STISGKRSER EGISGTGVGS
110 120 130 140 150
GDDHDEITPD RGYSRGTSDE EEDGGETSRK KLRLSKDQSA FLEETFKEHN
160 170 180 190 200
TLNPKQKLAL AKKLNLTARQ VEVWFQNRRA RTKLKQTEVD CEYLKRCVEK
210 220 230 240 250
LTEENRRLQK EAMELRTLKL SPQFYGQMTP PTTLIMCPSC ERVGGPSSSN
260 270 280
HHHNHRPVSI NPWVACAGQV AHGLNFEALR PRS
Length:283
Mass (Da):31,727
Last modified:December 1, 2000 - v2
Checksum:iBA594B82B9D85E64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB067629 mRNA. Translation: BAB63202.1.
AJ431183 mRNA. Translation: CAD24013.1.
AB018117 Genomic DNA. Translation: BAA97171.1.
CP002688 Genomic DNA. Translation: AED95503.1.
AF428450 mRNA. Translation: AAL16219.1.
AY052324 mRNA. Translation: AAK96517.1.
AY061904 mRNA. Translation: AAL31231.1.
U09335 mRNA. Translation: AAA56901.1.
PIRiT52368.
RefSeqiNP_199548.1. NM_124108.3.
UniGeneiAt.25127.

Genome annotation databases

EnsemblPlantsiAT5G47370.1; AT5G47370.1; AT5G47370.
GeneIDi834784.
GrameneiAT5G47370.1; AT5G47370.1; AT5G47370.
KEGGiath:AT5G47370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB067629 mRNA. Translation: BAB63202.1.
AJ431183 mRNA. Translation: CAD24013.1.
AB018117 Genomic DNA. Translation: BAA97171.1.
CP002688 Genomic DNA. Translation: AED95503.1.
AF428450 mRNA. Translation: AAL16219.1.
AY052324 mRNA. Translation: AAK96517.1.
AY061904 mRNA. Translation: AAL31231.1.
U09335 mRNA. Translation: AAA56901.1.
PIRiT52368.
RefSeqiNP_199548.1. NM_124108.3.
UniGeneiAt.25127.

3D structure databases

ProteinModelPortaliP46601.
SMRiP46601.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi20032. 10 interactors.
DIPiDIP-60613N.
IntActiP46601. 9 interactors.
STRINGi3702.AT5G47370.1.

PTM databases

iPTMnetiP46601.

Proteomic databases

PaxDbiP46601.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G47370.1; AT5G47370.1; AT5G47370.
GeneIDi834784.
GrameneiAT5G47370.1; AT5G47370.1; AT5G47370.
KEGGiath:AT5G47370.

Organism-specific databases

TAIRiAT5G47370.

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000241612.
InParanoidiP46601.
KOiK09338.
OMAiVSINPWV.
OrthoDBiEOG09360N3V.
PhylomeDBiP46601.

Miscellaneous databases

PROiP46601.

Gene expression databases

GenevisibleiP46601. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR006712. HD-ZIP_N.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003106. Leu_zip_homeo.
[Graphical view]
PfamiPF02183. HALZ. 1 hit.
PF04618. HD-ZIP_N. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00340. HALZ. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHAT2_ARATH
AccessioniPrimary (citable) accession number: P46601
Secondary accession number(s): Q546H4, Q9LVS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 1, 2000
Last modified: November 30, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.