P46592 (MNT2_CANAX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable mannosyltransferase MNT2
EC=2.4.1.-

Gene names

Name:

MNT2

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Possible glycosyltransferase.
Catalytic activity	Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
Sequence similarities	Belongs to the glycosyltransferase 15 family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological process	protein glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	mannosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 461	461	Probable mannosyltransferase MNT2		PRO_0000208251
Regions
	Compositional bias	65 – 69	5	Poly-Gln
	Compositional bias	108 – 112	5	Poly-Ser
	Compositional bias	128 – 131	4	Poly-Ser
Sites
	Active site	349	1	Nucleophile Potential

Sequences

	Sequence		Length	Mass (Da)
	P46592 [UniParc]. Last modified October 1, 1996. Version 2. Checksum: 9A374446C5116335	FASTA	461	54,562
	10 20 30 40 50 60 MKPSIFYSSR QPYLKYLAII LTTITIYVLT HSSYSADPNI NDVTTKPISE TVPQPPPQSP 70 80 90 100 110 120 SSPEQQQQQP ANQDQIVKVP EELKNKPQDL VVDNNKDQKP AVSGVPKSSS SSPQQQEKQD 130 140 150 160 170 180 TKKESENSSS SKDPVKPEKV KATFVTLARN SELYDLIKSI RNVEDRFNRK FNYDWVFLND 190 200 210 220 230 240 DDFTQEFKDL TTALVSGKTK YGKIPKEHWS YPDWIDLKRA EETRKNMKLQ KIIYGDSESY 250 260 270 280 290 300 RHMCRFESGF FWRHPLLDDY DWYWRVEPSI DIHCDLNYDL FKYMEDNNKV YGFTISIHEF 310 320 330 340 350 360 RATIPTLWDT TKKFIKENPQ YLAENNFMDF ISDDKGETYN LCHFWSNFEI ANLNFWRGEA 370 380 390 400 410 420 YRKYFDYLDQ TGGFFYERWG DAPIHSIAAA LFLPKDKIHY FDDVGYKHSV YTQCPLNPQF 430 440 450 460 RYEHKCHCNP DNDFTFRGYS CGKKYFEKMG LQKPKEWEKY Q

References

[1]	Buurman E.T., Gow N.A.R. Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CAI4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X89263 Genomic DNA. Translation: CAA61538.1.
PIR	S57713.
3D structure databases
ProteinModelPortal	P46592.
SMR	P46592. Positions 136-461.
ModBase	Search...
Protein family/group databases
CAZy	GT15. Glycosyltransferase Family 15.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002685. Glyco_trans_15. [Graphical view]
Pfam	PF01793. Glyco_transf_15. 1 hit. [Graphical view]
PIRSF	PIRSF018153. Glyco_trans_15. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MNT2_CANAX

Accession

Primary (citable) accession number: P46592

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	October 1, 1996
Last modified:	October 19, 2011
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program