P46589 (ADF1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adherence factor

Alternative name(s):
Adhesion and aggregation mediating surface antigen

Gene names

Name:	ADF1
Synonyms:	AAF1
ORF Names:	CaO19.7436

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	612 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function

Surface antigen mediating adhesion and aggregation in S.cerevisiae.

Ontologies

Keywords
Biological process	Cell adhesion
Gene Ontology (GO)
Biological process	adhesion to host Inferred from genetic interaction. Source: CGD cell-cell adhesion Inferred from direct assay. Source: CGD filamentous growth Inferred from mutant phenotype. Source: CGD
Cellular component	cytoplasm Inferred from genetic interaction. Source: CGD nucleus Inferred from genetic interaction. Source: CGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 612	612	Adherence factor		PRO_0000064451
Regions
	Compositional bias	64 – 69	6	Poly-Gln
	Compositional bias	100 – 103	4	Poly-Ser
	Compositional bias	117 – 134	18	Poly-Gln
	Compositional bias	269 – 272	4	Poly-Asn
	Compositional bias	517 – 520	4	Poly-Pro
	Compositional bias	579 – 582	4	Poly-Pro
	Compositional bias	596 – 605	10	Poly-Gln
Experimental info
	Sequence conflict	142	1	F → N in AAA62506. Ref.3
	Sequence conflict	451	1	T → I in AAA62506. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P46589 [UniParc]. Last modified October 1, 1996. Version 2. Checksum: 77B60E45C35C1B23	FASTA	612	68,794
	10 20 30 40 50 60 MSSFNSNSNP ANAQNLSSFQ FQPPKEDVIF DTHQMSLSVP QSRYYASSMM QQSQQGQPQS 70 80 90 100 110 120 QTSQQQQQQP FLMNIPPAFT QTQPQQMLYA MPPLQTQQPS SSSATTNNVV PPHHYNQQQS 130 140 150 160 170 180 QQQQQQQQQY QQMQPQPNNM QFFDNTIPNY LIMNQTISPS QTQTTAQPNI SYYNYSTQPQ 190 200 210 220 230 240 LQSAQPISHS QPQPQPQATQ PRSNRSRSQT SFSKPRGSRQ VSGSGRSTGA KKQSAITSGS 250 260 270 280 290 300 TGTGPARNAD TGMTSVANST STTTMTTTNN NNKLSVSAPV NVIYANLPER LQQVLPAPPL 310 320 330 340 350 360 SRAPVRPDVT VNLTSKRAKR KSKFTPEQDD MIVNLKKKGK SWVEIAEITG VGSYLAARNR 370 380 390 400 410 420 FQVIVGQQGN NNSSAWDNTD KLFLNQLLDA GEIEKWRFIC CELNKSTNKN FTDYECREMI 430 440 450 460 470 480 RQLFWLNPAS FGVNEETIIE SQKEKKLTEK TIEQREQQRK KRASANHSPP DSDSITNTNN 490 500 510 520 530 540 NQQEVKYIDP QYKNYQSQLM PNQNTGSGAT KISSTTPPPP SQALSNNVNT MNKNIVSSAL 550 560 570 580 590 600 GGTSFSQEQH SLHSNQHHHN HQQHPLIHHH QYQQQSSLPP PPTIPSTIPT SSLSIQQQQQ 610 QQQQQLYNKQ FY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Jiang W., Finkler A., Koltin Y. Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.
[3]	Edwards J.E. Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 35-612. Strain: ATCC 36082.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U44747 Genomic DNA. Translation: AAA86758.1. AACQ01000074 Genomic DNA. Translation: EAK97093.1. U18983 Genomic DNA. Translation: AAA62506.1.
RefSeq	XP_716097.1. XM_711004.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3642284.
KEGG	cal:CaO19.7436.
Organism-specific databases
CGD	CAL0005516. AAF1.
Phylogenomic databases
OMA	SSAWDNT.
PhylomeDB	P46589.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ADF1_CANAL

Accession

Primary (citable) accession number: P46589
Secondary accession number(s): Q5A2X5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	October 1, 1996
Last modified:	January 25, 2012
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program