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P46558 (KICB1_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Choline kinase B1

EC=2.7.1.32
Gene names
Name:ckb-1
ORF Names:B0285.8
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + choline = ADP + phosphocholine.

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the choline/ethanolamine kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371Choline kinase B1
PRO_0000206232

Sequences

Sequence LengthMass (Da)Tools
P46558 [UniParc].

Last modified March 15, 2004. Version 2.
Checksum: 035F6EE53F026709

FASTA37142,786
        10         20         30         40         50         60 
MRPIEKFFTE NAPDSDLVIE KVIEFGIDFL GGEWKNVKKN EVKVTTILGG QSNHMFHVTS 

        70         80         90        100        110        120 
STSATPYLLR IHRQGPSHVF MDTVNFAIFS ERGLGPKLYG FFDGGRMEEF LPSRTLDSDC 

       130        140        150        160        170        180 
ILDPEISRRV GAVYPKYHAI DVPVSKKRRC FQVMRESLKE YQDLGGGDYE IKPTTVTYSE 

       190        200        210        220        230        240 
HPKKISMDDL YKEIDFMEKW TNELFEDTVV FCHNDLASSN ILELNSTKEL VLIDWEFGSY 

       250        260        270        280        290        300 
NCRGFDLAMH LAETAADFRD STPPGIRISE ELTDNPPNLQ GFCEAYVDAD NKLKNRVPSN 

       310        320        330        340        350        360 
RDLEVSNLIC ECQFFWPITQ LFWACFVMKL ALLKYNCGVD MDVQAQDRFA VYWHLKERTR 

       370 
KIYEDLKKGT C 

« Hide

References

« Hide 'large scale' references
[1]"Multiple isoforms of choline kinase from Caenorhabditis elegans: cloning, expression, purification, and characterization."
Gee P., Kent C.
Biochim. Biophys. Acta 1648:33-42(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY158690 mRNA. Translation: AAN41642.1.
Z34533 Genomic DNA. Translation: CAA84300.2.
PIRT18695.
RefSeqNP_497879.2. NM_065478.2.
UniGeneCel.20658.

3D structure databases

ProteinModelPortalP46558.
SMRP46558. Positions 11-362.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid46770. 1 interaction.
STRING6239.B0285.8.

Proteomic databases

PaxDbP46558.
PRIDEP46558.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaB0285.8; B0285.8; B0285.8.
GeneID181904.
KEGGcel:CELE_B0285.8.
UCSCB0285.8. c. elegans.

Organism-specific databases

CTD181904.
WormBaseB0285.8; CE33590; WBGene00000511; ckb-1.

Phylogenomic databases

eggNOGCOG0510.
HOGENOMHOG000015981.
InParanoidP46558.
OMADINIRAR.
PhylomeDBP46558.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
ProtoNetSearch...

Other

NextBio915744.

Entry information

Entry nameKICB1_CAEEL
AccessionPrimary (citable) accession number: P46558
Secondary accession number(s): Q8IS24
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: March 15, 2004
Last modified: April 16, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase