Reviewed, UniProtKB/Swiss-Prot P46513 (CAH2_FLALI)

Names and origin

Protein names	Recommended name:     Carbonic anhydrase 2     EC=4.2.1.1 Alternative name(s):     Carbonate dehydratase 2
Organism	Flaveria linearis (Narrowleaf yellowtops)
Taxonomic identifier	4225 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Tageteae › Flaveria

Protein attributes

Sequence length	190 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Reversible hydration of carbon dioxide.
Catalytic activity	H2CO3 = CO2 + H2O.
Subunit structure	Homohexamer By similarity.
Subcellular location	Cytoplasm Potential.
Domain	Possesses a transit-like peptide, but it is proposed that this peptide is not removed and that therefore the enzyme stays in the cytoplasm instead of going to the chloroplast By similarity.
Sequence similarities	Belongs to the beta-class carbonic anhydrase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Zinc
Molecular function	Lyase
Gene Ontology (GO)
Biological process	carbon utilization Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	carbonate dehydratase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 190	›190	Carbonic anhydrase 2		PRO_0000077456
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P46513-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: F07686E36A46D782	FASTA	190	20,585
	10 20 30 40 50 60 NPTLYGELAK GQSPKFLVFA CSDSRVCPSH ILDFQPGEAF VVRNIANMVP PYDTIKHSGA 70 80 90 100 110 120 GAAIEYAVLH LKVENIVVIG HSCCGGIKGL MSIPDDGTPA SDFIEQWVKL GLPAKSKVKA 130 140 150 160 170 180 NCNNLEFADL CTKCEKEAVN VSLGNLLTYP FVRDALVNKK LSLKGAHYDF VNGAFDLWNL 190 DFGISPSLLQ

References

[1]	"Molecular comparison of carbonic anhydrase from Flaveria species demonstrating different photosynthetic pathways." Ludwig M., Burnell J.N. Plant Mol. Biol. 29:353-365(1995) [PubMed: 7579185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U19740 mRNA. Translation: AAA86994.1.
PIR	T10740.
3D structure databases
HSSP	HSSP built from PDB template 1EKJ based on UniProtKB P17067.
SMR	P46513. Positions 1-188.
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.2.1.1. 276006.
Family and domain databases
InterPro	IPR001765. Carbonic_anhydrase. IPR015892. Carbonic_anhydrase_CS. [Graphical view]
Gene3D	G3DSA:3.40.1050.10. CO_anhd_prok_pln. 1 hit.
PANTHER	PTHR11002. Carbonic_anhydrase. 1 hit.
Pfam	PF00484. Pro_CA. 1 hit. [Graphical view]
PROSITE	PS00704. PROK_CO2_ANHYDRASE_1. 1 hit. PS00705. PROK_CO2_ANHYDRASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAH2_FLALI

Accession

Primary (citable) accession number: P46513

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)