Reviewed, UniProtKB/Swiss-Prot P46511 (CAHX_FLABR)

Names and origin

Protein names	Recommended name:     Carbonic anhydrase     EC=4.2.1.1 Alternative name(s):     Carbonate dehydratase
Organism	Flaveria brownii (Brown's yellowtops)
Taxonomic identifier	33111 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Tageteae › Flaveria

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Reversible hydration of carbon dioxide.
Catalytic activity	H2CO3 = CO2 + H2O.
Subcellular location	Cytoplasm Potential.
Domain	Possesses a transit-like peptide, but it is proposed that this peptide is not removed and that therefore the enzyme stays in the cytoplasm instead of going to the chloroplast By similarity.
Sequence similarities	Belongs to the beta-class carbonic anhydrase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Zinc
Molecular function	Lyase
Gene Ontology (GO)
Biological process	carbon utilization Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	carbonate dehydratase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	Carbonic anhydrase		PRO_0000077454
Regions
	Region	1 – 109	109	Chloroplast transit peptide-like
	Compositional bias	41 – 47	7	Poly-Ser

Sequences

	Sequence		Length	Mass (Da)
	P46511-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 94C7B5CBB111D768	FASTA	330	35,547
	10 20 30 40 50 60 MSTASAFATN VPSFVNASSL KKSSTSSARS GVLSAKFTCN SSSSSSSATP PSLIRNEPVF 70 80 90 100 110 120 AAPAPIITPN WTEDGNESYE EAIDALKKML IEKGELEPVA AARIDQITAQ AAAPDTKAPF 130 140 150 160 170 180 DPVERIKSGF VKFKTEKFVT NPALYDELAK GQSPKFMVFA CSDSRVCPSH VLDFQPGEAF 190 200 210 220 230 240 VVRNVANMVP PFDKTKYSGV GAAVEYAVLH LKVQEIFVIG HSRCGGIKGL MTFPDEGPHS 250 260 270 280 290 300 TDFIEDWVKV CLPAKSKVVA EHNGTHLDDQ CVLCEKEAVN VSLGNLLTYP FVRDGLRNNT 310 320 330 LALKGGHYDF VNGTFELWAL DFGLSSPTSV

References

[1]	"Molecular comparison of carbonic anhydrase from Flaveria species demonstrating different photosynthetic pathways." Ludwig M., Burnell J.N. Plant Mol. Biol. 29:353-365(1995) [PubMed: 7579185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Leaf.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U08402 mRNA. Translation: AAA86942.1.
PIR	S61882.
3D structure databases
SMR	P46511. Positions 124-330.
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.2.1.1. 190863.
Family and domain databases
InterPro	IPR001765. Carbonic_anhydrase. IPR015892. Carbonic_anhydrase_CS. [Graphical view]
Gene3D	G3DSA:3.40.1050.10. CO_anhd_prok_pln. 1 hit.
PANTHER	PTHR11002. Carbonic_anhydrase. 1 hit.
Pfam	PF00484. Pro_CA. 1 hit. [Graphical view]
PROSITE	PS00704. PROK_CO2_ANHYDRASE_1. 1 hit. PS00705. PROK_CO2_ANHYDRASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAHX_FLABR

Accession

Primary (citable) accession number: P46511

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 24, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)