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P46479 (G6PI_CALFI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:PGI
OrganismCalanus finmarchicus (Calanus tonsus)
Taxonomic identifier6837 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMaxillopodaCopepodaCalanoidaCalanidaeCalanus

Protein attributes

Sequence length304 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›304›304Glucose-6-phosphate isomerase
PRO_0000180542

Sites

Active site1461Proton donor By similarity
Active site1771 By similarity

Experimental info

Non-terminal residue11
Non-terminal residue3041

Sequences

Sequence LengthMass (Da)Tools
P46479 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 520F95811054FCF7

FASTA30434,460
        10         20         30         40         50         60 
FTTQETITNA NTAKQWFLKS AKDSKFVANH FVALSTNAKL VQEFGIDKAN MFEFWDWVGG 

        70         80         90        100        110        120 
RYSLWSAIGM SIALNIGFEN FEHLLSGAHW MDNHFKSTPI ERNIPVILAV LGIWYGNFYG 

       130        140        150        160        170        180 
AETQALLPYD QYMHRFAAYF QQGDMESNGK YVVRAGDKVN YSTGPIVWGE PGTNGQHAFY 

       190        200        210        220        230        240 
QLIHQVPHHP CDFNSPVKSH NSELRDGLHH TILLSNFLAQ TEALMKGKDR QTVEKELKAA 

       250        260        270        280        290        300 
GKSEDEIKSI GPHKEFTGNR PTNSIMVDTV TPFTLGAMIA MYEHKIFTQG IIWDINSYDQ 


WGVE 

« Hide

References

[1]"Nuclear genes from the copepod Calanus finmarchicus."
Crawford D.L.
Mol. Mar. Biol. Biotechnol. 4:241-247(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U21239 mRNA. Translation: AAA85286.1.

3D structure databases

ProteinModelPortalP46479.
SMRP46479. Positions 1-304.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP46479.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CALFI
AccessionPrimary (citable) accession number: P46479
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways