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P46440 (GSTF2_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase APIC

EC=2.5.1.18
Alternative name(s):
GST class-phi
Gene names
Name:APIC
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Induction

By aluminum stress and phosphate starvation.

Sequence similarities

Belongs to the GST superfamily. Phi family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processStress response
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213Glutathione S-transferase APIC
PRO_0000185857

Regions

Domain1 – 8282GST N-terminal
Domain89 – 213125GST C-terminal
Region40 – 412Glutathione binding By similarity
Region53 – 542Glutathione binding By similarity
Region66 – 672Glutathione binding By similarity

Sites

Binding site111Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
P46440 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: EFFBE1A23094037B

FASTA21324,113
        10         20         30         40         50         60 
MAIKVHGSPM STATMRVAAC LIEKDLDFEL VPVDMVSGEH KKHPYLSLNP FGQVPAFEDG 

        70         80         90        100        110        120 
DLKLFESRAI TQYIAHVYAD NGYQLILQDP KKMPIMSVWM EVEGQKFEPH ASKLTWELGI 

       130        140        150        160        170        180 
KPIIGMTTDD DAVKESEVQL SKVLDIYETR LAESKYLGGD SFTLVDLHHI PNIYYLMSTK 

       190        200        210 
VKEVFDSRPR VSAWCADILA RPAWVKGLEK LQK 

« Hide

References

[1]"Cloning and sequencing of the cDNAs induced by aluminium treatment and Pi starvation in cultured tobacco cells."
Ezaki B., Yamamoto Y., Matsumoto H.
Physiol. Plantarum 93:11-18(1995)
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Samsun.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D29680 mRNA. Translation: BAA06150.1.

3D structure databases

ProteinModelPortalP46440.
SMRP46440. Positions 2-206.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTF2_TOBAC
AccessionPrimary (citable) accession number: P46440
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families