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Protein

Glutathione S-transferase 3

Gene

GST3

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the detoxification of certain herbicides.

Caution

Was originally (Ref. 1) thought to be a glyoxalase I.Curated

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei13GlutathioneBy similarity1
Binding sitei54Glutathione; via amide nitrogen and carbonyl oxygenBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase 3 (EC:2.5.1.18)
Gene namesi
Name:GST3
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Chromosome 15

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001858731 – 219Glutathione S-transferase 3Add BLAST219

Proteomic databases

PRIDEiP46417

Expressioni

Gene expression databases

GenevisibleiP46417 GM

Interactioni

Subunit structurei

Homodimer. degradation; (R)-lactate from methylglyoxal: step 1/2.1 Publication

Protein-protein interaction databases

STRINGi3847.GLYMA15G40290.1

Structurei

3D structure databases

ProteinModelPortaliP46417
SMRiP46417
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 82GST N-terminalAdd BLAST80
Domaini88 – 216GST C-terminalAdd BLAST129

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni66 – 67Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. HSP26 family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
InParanoidiP46417
KOiK00799
OMAiRCMERET
OrthoDBiEOG09360PCQ

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

P46417-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDEVVLLDT WASMYGMRAR IALAEKGVRY EYKEENLMNR SPLLLQMNPI
60 70 80 90 100
HKKIPVLIHN GKPICESAII VQYIDEVWND KSPLMPSDPY KRSQARFWVD
110 120 130 140 150
YIDKKIYDTW KKMWLSKGEE HEEGKKELIS IFKQLEETLT DKPFYGDDTF
160 170 180 190 200
GFVDLCLITF SSWFYTYETY GNFKMEEECP KLMAWVKRCM ERETVSNTLP
210
DAKKVYGLIV ELQKTLESK
Length:219
Mass (Da):25,901
Last modified:November 1, 1995 - v1
Checksum:i6A2E46B759476A8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68819 mRNA Translation: CAA48717.1
PIRiS47177
RefSeqiNP_001236181.1, NM_001249252.2
UniGeneiGma.1560

Genome annotation databases

EnsemblPlantsiKRH13625; KRH13625; GLYMA_15G252200
GeneIDi547925
GrameneiKRH13625; KRH13625; GLYMA_15G252200
KEGGigmx:547925

Similar proteinsi

Entry informationi

Entry nameiGSTX3_SOYBN
AccessioniPrimary (citable) accession number: P46417
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 25, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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