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Protein

Single-stranded DNA-binding protein

Gene

ssb

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded DNA-binding proteinUniRule annotation
Short name:
SSBUniRule annotation
Gene namesi
Name:ssb
Ordered Locus Names:ML2684
ORF Names:MLCB1913.20c
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000806 Componenti: Chromosome

Organism-specific databases

LepromaiML2684.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 168168Single-stranded DNA-binding proteinPRO_0000096067Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi272631.ML2684.

Structurei

Secondary structure

1
168
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 1611Combined sources
Beta strandi27 – 359Combined sources
Beta strandi53 – 608Combined sources
Helixi61 – 7010Combined sources
Beta strandi76 – 8813Combined sources
Beta strandi96 – 10813Combined sources
Beta strandi111 – 1188Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3AFPX-ray2.05A/B1-168[»]
3AFQX-ray2.80A/B/C/D1-168[»]
ProteinModelPortaliP46390.
SMRiP46390. Positions 2-120.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP46390.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 110110SSBUniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SSB domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107YH6. Bacteria.
COG0629. LUCA.
HOGENOMiHOG000106485.
KOiK03111.
OMAiSTPRMFD.
OrthoDBiPOG091H00DP.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46390-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGDTTITIV GNLTADPELR FTSSGAAVVN FTVASTPRIY DRQSGEWKDG
60 70 80 90 100
EALFLRCNIW REAAENVAES LTRGARVIVT GRLKQRSFET REGEKRTVVE
110 120 130 140 150
VEVDEIGPSL RYATAKVNKA SRSGGGGGGF GSGSRQAPAQ MSGGVGDDPW
160
GSAPTSGSFG VGDEEPPF
Length:168
Mass (Da):17,701
Last modified:April 27, 2001 - v2
Checksum:i077C62E430623658
GO

Sequence cautioni

The sequence AAB53120 differs from that shown. Reason: Frameshift at position 137. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39923 Genomic DNA. Translation: AAB53120.1. Frameshift.
AL022118 Genomic DNA. Translation: CAA17953.1.
AL583926 Genomic DNA. Translation: CAC32216.1.
PIRiB87245.
RefSeqiNP_302712.1. NC_002677.1.
WP_010909031.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC32216; CAC32216; CAC32216.
GeneIDi908269.
KEGGimle:ML2684.
PATRICi18060525. VBIMycLep78757_5176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39923 Genomic DNA. Translation: AAB53120.1. Frameshift.
AL022118 Genomic DNA. Translation: CAA17953.1.
AL583926 Genomic DNA. Translation: CAC32216.1.
PIRiB87245.
RefSeqiNP_302712.1. NC_002677.1.
WP_010909031.1. NC_002677.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3AFPX-ray2.05A/B1-168[»]
3AFQX-ray2.80A/B/C/D1-168[»]
ProteinModelPortaliP46390.
SMRiP46390. Positions 2-120.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272631.ML2684.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC32216; CAC32216; CAC32216.
GeneIDi908269.
KEGGimle:ML2684.
PATRICi18060525. VBIMycLep78757_5176.

Organism-specific databases

LepromaiML2684.

Phylogenomic databases

eggNOGiENOG4107YH6. Bacteria.
COG0629. LUCA.
HOGENOMiHOG000106485.
KOiK03111.
OMAiSTPRMFD.
OrthoDBiPOG091H00DP.

Miscellaneous databases

EvolutionaryTraceiP46390.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00984. SSB. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR000424. Primosome_PriB/ssb.
IPR011344. ssDNA-bd.
[Graphical view]
PANTHERiPTHR10302. PTHR10302. 1 hit.
PfamiPF00436. SSB. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00621. ssb. 1 hit.
PROSITEiPS50935. SSB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSSB_MYCLE
AccessioniPrimary (citable) accession number: P46390
Secondary accession number(s): O53126
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: April 27, 2001
Last modified: September 7, 2016
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.