P46364 (XYLB_ACIGB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Aryl-alcohol dehydrogenase EC=1.1.1.90 Alternative name(s): Benzyl alcohol dehydrogenase Short name=BADH
Organism	Acinetobacter genomosp. 11
Taxonomic identifier	106649 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	42 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Oxidizes primary alcohols with an aromatic or cyclohex-1-ene ring. It is highly specific for benzyl alcohol.
Catalytic activity	An aromatic alcohol + NAD+ = an aromatic aldehyde + NADH.
Cofactor	Binds 2 zinc ions per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Ligand	Metal-binding NAD Zinc
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	aryl-alcohol dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›42	›42	Aryl-alcohol dehydrogenase		PRO_0000160828
Experimental info
	Non-terminal residue	42	1

Sequences

	Sequence		Length	Mass (Da)
	P46364 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 65615B99D4468ACF	FASTA	42	4,508
	10 20 30 40 SELKDIIAAV TPCKGADFEL QALKIRQPQG DEVLVKXXAT GM

References

[1]

"Comparison of benzyl alcohol dehydrogenases and benzaldehyde dehydrogenases from the benzyl alcohol and mandelate pathways in Acinetobacter calcoaceticus and from the TOL-plasmid-encoded toluene pathway in Pseudomonas putida. N-terminal amino acid sequences, amino acid compositions and immunological cross-reactions." Chalmers R.M., Keen J.N., Fewson C.A. Biochem. J. 273:99-107(1991) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: ATCC 11171 / NCIB 8250 / CIP 63.46 / B94.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00059. ADH_ZINC. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLB_ACIGB

Accession

Primary (citable) accession number: P46364

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program