Reviewed, UniProtKB/Swiss-Prot P46364 (XYLB_ACIGB)

Names and origin

Protein names	Recommended name:     Aryl-alcohol dehydrogenase     EC=1.1.1.90 Alternative name(s):     Benzyl alcohol dehydrogenase       Short name=BADH
Organism	Acinetobacter genomosp. 11
Taxonomic identifier	106649 [NCBI]
Taxonomic lineage	Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	42 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Oxidizes primary alcohols with an aromatic or cyclohex-1-ene ring. It is highly specific for benzyl alcohol.
Catalytic activity	An aromatic alcohol + NAD(+) = an aromatic aldehyde + NADH.
Cofactor	Binds 2 zinc ions per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Ligand	Metal-binding NAD Zinc
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aryl-alcohol dehydrogenase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›42	›42	Aryl-alcohol dehydrogenase		PRO_0000160828
Experimental info
	Non-terminal residue	42	1

Sequences

	Sequence		Length	Mass (Da)
	P46364-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 65615B99D4468ACF	FASTA	42	4,508
	10 20 30 40 SELKDIIAAV TPCKGADFEL QALKIRQPQG DEVLVKXXAT GM

References

[1]

"Comparison of benzyl alcohol dehydrogenases and benzaldehyde dehydrogenases from the benzyl alcohol and mandelate pathways in Acinetobacter calcoaceticus and from the TOL-plasmid-encoded toluene pathway in Pseudomonas putida. N-terminal amino acid sequences, amino acid compositions and immunological cross-reactions." Chalmers R.M., Keen J.N., Fewson C.A. Biochem. J. 273:99-107(1991) [PubMed: 1989592] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: ATCC 11171 / NCIB 8250 / CIP 63.46 / B94.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR002328. AlcDHase_Zn_CS. [Graphical view]
PROSITE	PS00059. ADH_ZINC. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLB_ACIGB

Accession

Primary (citable) accession number: P46364

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 4, 2008
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)