Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative aldehyde dehydrogenase AldX

Gene

aldX

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei214PROSITE-ProRule annotation1
Active sitei248PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBSUB:BSU39860-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase AldXPROSITE-ProRule annotation (EC:1.2.1.3PROSITE-ProRule annotation)
Gene namesi
Name:aldX
Synonyms:yxaS, yxbE
Ordered Locus Names:BSU39860
ORF Names:VE7FR
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

No effect on vanillin degradation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564461 – 445Putative aldehyde dehydrogenase AldXAdd BLAST445

Proteomic databases

PaxDbiP46329

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021496

Structurei

3D structure databases

ProteinModelPortaliP46329
SMRiP46329
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271515
InParanoidiP46329
KOiK00128
OMAiQKLPEWA
PhylomeDBiP46329

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
IPR012394 Aldehyde_DH_NAD(P)
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
PIRSFiPIRSF036492 ALDH, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

P46329-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQQVKDDIQ RVFQLQKKQQ KALRASTAEQ RREKLQRFLD SVIAHEEEII
60 70 80 90 100
EAIRKDVRKP YHEVKKAEIE GTKKAIRDNM NNLEQWMAPK EVGSSLSPDA
110 120 130 140 150
NGILMYEPKG VTLILGPWNY PFMLTMAPLA ASLAAGNSAI VKLSDFTMNT
160 170 180 190 200
SNIAAKVIRD AFDEKEVAIF EGEVEVATEL LDQPFDHIFF TGSTNVGKIV
210 220 230 240 250
MTAAAKHLAS VTLELGGKSP TIIDSEYDLM DAAKKIAVGK FVNAGQTCIA
260 270 280 290 300
PDYLFIKKDV QDRFAGILQT VVNAGFMEDD HTPDRSKFTQ IVNDRNFNRV
310 320 330 340 350
KDLFDDAIER GAEVVFGGVF DASDRTISPT VLKNVTPDMK IMQEEIFASI
360 370 380 390 400
LPMMNYEDID EVIDYVNDRD KPLALYVFSK NQDLIDNVLQ HTTSGNAAIN
410 420 430 440
DVVVHFSDVN LPFGGVNTSG IGSYHGVYGF KEFSHEKGVF IQAAE
Length:445
Mass (Da):49,571
Last modified:July 28, 2009 - v2
Checksum:iB705ABD3EFF43A2E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti163D → N in BAA21599 (PubMed:7584049).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB005554 Genomic DNA Translation: BAA21599.1
AL009126 Genomic DNA Translation: CAB16022.2
PIRiB69584
RefSeqiNP_391865.2, NC_000964.3
WP_003243415.1, NZ_JNCM01000034.1

Genome annotation databases

EnsemblBacteriaiCAB16022; CAB16022; BSU39860
GeneIDi937653
KEGGibsu:BSU39860
PATRICifig|224308.179.peg.4312

Similar proteinsi

Entry informationi

Entry nameiALDH3_BACSU
AccessioniPrimary (citable) accession number: P46329
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 28, 2009
Last modified: April 25, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health