P46269 (QCR8_SOLTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Cytochrome b-c1 complex subunit 8 Alternative name(s): Complex III subunit 8 Complex III subunit VII Ubiquinol-cytochrome c reductase complex 8.2 kDa protein Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
Organism	Solanum tuberosum (Potato) [Reference proteome]
Taxonomic identifier	4113 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
Subunit structure	Plants bc1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the UQCRQ/QCR8 family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.1
	Chain	2 – 72	71	Cytochrome b-c1 complex subunit 8		PRO_0000193548
Experimental info
	Sequence conflict	15	1	I → L AA sequence Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P46269 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 3AC5C12019223DA6	FASTA	72	8,317
	10 20 30 40 50 60 MGKQPVKLKA VVYAISPFQQ KIMPGLWKDL PGKIHHKVSE NWISATLLLG PLVGTYSYVQ 70 HFLEKEKLEH RY

References

[1]	"Primary structure, cell-free synthesis and mitochondrial targeting of the 8.2 kDa protein of cytochrome c reductase from potato." Braun H.-P., Kruft V., Schmitz U.K. Biochim. Biophys. Acta 1188:367-372(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-28. Strain: cv. Bintje. Tissue: Tuber.
[2]	"Molecular identification of the ten subunits of cytochrome-c reductase from potato mitochondria." Braun H.-P., Kruft V., Schmitz U.K. Planta 193:99-106(1994) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 9-28 AND 67-72. Strain: cv. Hansa. Tissue: Tuber.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X79275 mRNA. Translation: CAA55862.1.
PIR	T07370.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR020101. Cyt_b-c1_8-plants. [Graphical view]
Pfam	PF10890. DUF2741. 1 hit. [Graphical view]
ProDom	PD056240. Cytochrome_b-c1_8. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

QCR8_SOLTU

Accession

Primary (citable) accession number: P46269

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program