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P46257 (ALF2_PEA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase, cytoplasmic isozyme 2

EC=4.1.2.13
OrganismPisum sativum (Garden pea)
Taxonomic identifier3888 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Fructose-bisphosphate aldolase, cytoplasmic isozyme 2
PRO_0000216924

Sites

Active site1841Proton acceptor By similarity
Active site2261Schiff-base intermediate with dihydroxyacetone-P By similarity
Binding site521Substrate By similarity
Binding site1431Substrate By similarity
Site3591Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
P46257 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: C0CAB16E9CC1B9EF

FASTA35938,491
        10         20         30         40         50         60 
MSHFKSKYHD ELIANAAYIG TPGKGILAAD ESTGTIGKRL SSINVENVES NRQALRELLF 

        70         80         90        100        110        120 
TASWLFLQYL SGVILFEETL YQKTAAGKPF VDVLNEAGVL PGIKVDKGTV ELAGTDGETT 

       130        140        150        160        170        180 
TQGLDGLGAR CRKYYEAGAR FAKWRAVLKI GANEPSEHSI HENAYGLARY AVICQENGLV 

       190        200        210        220        230        240 
PIVEPEILVD GSHDILKCAA ITERVLAATY KALSDHHVIL EGTLLKPNMV TPGSDAPKVA 

       250        260        270        280        290        300 
PEVIAEHTVR ALQRTVPAAV PAVVFLSGGQ SEEEASVNLN AINQIKGKKP WTLSFSFGRA 

       310        320        330        340        350 
LQQSTLKAWG GKTENVKAAQ DALLTRAKAN SEATLGTYKG ASNLGAGASE SLHVKDYKY 

« Hide

References

[1]Pelzer-Reith B., Schnarrenberger C.
Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X89829 Genomic DNA. Translation: CAA61947.1.
PIRS58167.

3D structure databases

ProteinModelPortalP46257.
SMRP46257. Positions 11-359.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP46257.
ProMEXP46257.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

SABIO-RKP46257.
UniPathwayUPA00109; UER00183.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
[Graphical view]
PANTHERPTHR11627. PTHR11627. 1 hit.
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF2_PEA
AccessionPrimary (citable) accession number: P46257
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways