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P46257

- ALF2_PEA

UniProt

P46257 - ALF2_PEA

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Protein
Fructose-bisphosphate aldolase, cytoplasmic isozyme 2
Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei52 – 521Substrate By similarity
Binding sitei143 – 1431Substrate By similarity
Active sitei184 – 1841Proton acceptor By similarity
Active sitei226 – 2261Schiff-base intermediate with dihydroxyacetone-P By similarity
Sitei359 – 3591Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate By similarity

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

SABIO-RKP46257.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase, cytoplasmic isozyme 2 (EC:4.1.2.13)
OrganismiPisum sativum (Garden pea)
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 359359Fructose-bisphosphate aldolase, cytoplasmic isozyme 2
PRO_0000216924Add
BLAST

Proteomic databases

PRIDEiP46257.
ProMEXiP46257.

Structurei

3D structure databases

ProteinModelPortaliP46257.
SMRiP46257. Positions 11-359.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEiPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46257-1 [UniParc]FASTAAdd to Basket

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MSHFKSKYHD ELIANAAYIG TPGKGILAAD ESTGTIGKRL SSINVENVES    50
NRQALRELLF TASWLFLQYL SGVILFEETL YQKTAAGKPF VDVLNEAGVL 100
PGIKVDKGTV ELAGTDGETT TQGLDGLGAR CRKYYEAGAR FAKWRAVLKI 150
GANEPSEHSI HENAYGLARY AVICQENGLV PIVEPEILVD GSHDILKCAA 200
ITERVLAATY KALSDHHVIL EGTLLKPNMV TPGSDAPKVA PEVIAEHTVR 250
ALQRTVPAAV PAVVFLSGGQ SEEEASVNLN AINQIKGKKP WTLSFSFGRA 300
LQQSTLKAWG GKTENVKAAQ DALLTRAKAN SEATLGTYKG ASNLGAGASE 350
SLHVKDYKY 359
Length:359
Mass (Da):38,491
Last modified:November 1, 1995 - v1
Checksum:iC0CAB16E9CC1B9EF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X89829 Genomic DNA. Translation: CAA61947.1.
PIRiS58167.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X89829 Genomic DNA. Translation: CAA61947.1 .
PIRi S58167.

3D structure databases

ProteinModelPortali P46257.
SMRi P46257. Positions 11-359.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P46257.
ProMEXi P46257.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
SABIO-RK P46257.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
PROSITEi PS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Pelzer-Reith B., Schnarrenberger C.
    Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Leaf.

Entry informationi

Entry nameiALF2_PEA
AccessioniPrimary (citable) accession number: P46257
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 3, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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