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P46256

- ALF1_PEA

UniProt

P46256 - ALF1_PEA

Protein

Fructose-bisphosphate aldolase, cytoplasmic isozyme 1

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei52 – 521SubstrateBy similarity
    Binding sitei142 – 1421SubstrateBy similarity
    Active sitei183 – 1831Proton acceptorBy similarity
    Active sitei225 – 2251Schiff-base intermediate with dihydroxyacetone-PBy similarity
    Sitei357 – 3571Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphateBy similarity

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    SABIO-RKP46256.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase, cytoplasmic isozyme 1 (EC:4.1.2.13)
    OrganismiPisum sativum (Garden pea)
    Taxonomic identifieri3888 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 357357Fructose-bisphosphate aldolase, cytoplasmic isozyme 1PRO_0000216923Add
    BLAST

    Proteomic databases

    PRIDEiP46256.
    ProMEXiP46256.

    Structurei

    3D structure databases

    ProteinModelPortaliP46256.
    SMRiP46256. Positions 10-337.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]
    PROSITEiPS00158. ALDOLASE_CLASS_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P46256-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAFVGKYAD ELIKNAKYIA TPGKGILAAD ESTGTIGKRL ASINVENIEA    50
    NRQALRELLF TSPNALQYLS GVILFEETLY QKSSEGKPFV EILQENNVIP 100
    GIKVDKGVVE LAGTDGETTT QGFDSLGARC QQYYKAGARF AKWRAVLKIG 150
    PNEPSELSIQ QNAQGLARYA IICQENGLVL FVEPEILTDG SHDIAKCAAV 200
    TETVLAACYK ALNDQHVLLE GTLLKPNMVT PGSDSPKVSP EVIGEYTVNA 250
    LRRTVPAAVP GIVFLSGGQS EEQATLNLNA MNKFDVVKPW TLSFSFGRAL 300
    QQSTLKTWSG KKENVGKAQD VFLARCKANS EATLGKYGGG SGTGLASESL 350
    HVKDYKY 357
    Length:357
    Mass (Da):38,446
    Last modified:November 1, 1995 - v1
    Checksum:iBB30E70BA0401D61
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X89828 mRNA. Translation: CAA61946.1.
    PIRiS58168.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X89828 mRNA. Translation: CAA61946.1 .
    PIRi S58168.

    3D structure databases

    ProteinModelPortali P46256.
    SMRi P46256. Positions 10-337.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P46256.
    ProMEXi P46256.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    SABIO-RK P46256.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    PROSITEi PS00158. ALDOLASE_CLASS_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Pelzer-Reith B., Schnarrenberger C.
      Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Leaf.

    Entry informationi

    Entry nameiALF1_PEA
    AccessioniPrimary (citable) accession number: P46256
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3