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P46250

- SEC14_CANAL

UniProt

P46250 - SEC14_CANAL

Protein

SEC14 cytosolic factor

Gene

SEC14

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro By similarity.By similarity

    GO - Molecular functioni

    1. phosphatidylinositol transporter activity Source: CGD

    GO - Biological processi

    1. CDP-choline pathway Source: CGD
    2. cellular response to drug Source: CGD
    3. phospholipid transport Source: GOC
    4. post-Golgi vesicle-mediated transport Source: CGD
    5. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SEC14 cytosolic factor
    Alternative name(s):
    Phosphatidylinositol/phosphatidylcholine transfer protein
    Short name:
    PI/PC TP
    Gene namesi
    Name:SEC14
    ORF Names:CaO19.8556, CaO19.941
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0003685. SEC14.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi apparatus Source: CGD
    2. Golgi membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 301301SEC14 cytosolic factorPRO_0000210739Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0003685.

    Structurei

    3D structure databases

    ProteinModelPortaliP46250.
    SMRiP46250. Positions 7-296.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini99 – 272174CRAL-TRIOPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 CRAL-TRIO domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG309458.
    OrthoDBiEOG761C55.

    Family and domain databases

    Gene3Di3.40.525.10. 1 hit.
    InterProiIPR001071. CRAL-bd_toc_tran.
    IPR001251. CRAL-TRIO_dom.
    IPR011074. CRAL/TRIO_N_dom.
    [Graphical view]
    PfamiPF00650. CRAL_TRIO. 1 hit.
    PF03765. CRAL_TRIO_N. 1 hit.
    [Graphical view]
    PRINTSiPR00180. CRETINALDHBP.
    SMARTiSM01100. CRAL_TRIO_N. 1 hit.
    SM00516. SEC14. 1 hit.
    [Graphical view]
    SUPFAMiSSF46938. SSF46938. 1 hit.
    SSF52087. SSF52087. 1 hit.
    PROSITEiPS50191. CRAL_TRIO. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P46250-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTMTTEEIL ASYPQITAPT DQTGYTSNLT PEQKTTLDIF RQQLTELGYK    50
    DRLDDASLLR FLRARKFDIQ KAIDMFVACE KWREDFGVNT ILKDFHYEEK 100
    PIVAKMYPTY YHKTDKDGRP VYFEELGKVD LVKMLKITTQ ERMLKNLVWE 150
    YEAMCQYRLP ACSRKAGYLV ETSCTVLDLS GISVTSAYNV IGYVREASKI 200
    GQDYYPERMG KFYLINAPFG FSTAFKLFKP FLDPVTVSKI HILGYSYKKE 250
    LLKQIPPQNL PVKFGGMSDV SDDDLLLKDV GPWRDPEFIG PEGECPRAYN 300
    I 301
    Length:301
    Mass (Da):34,709
    Last modified:November 1, 1995 - v1
    Checksum:i1F194A8EA8B525BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X81937 Genomic DNA. Translation: CAA57490.1.
    U61975 mRNA. Translation: AAB41491.1.
    AACQ01000063 Genomic DNA. Translation: EAK97793.1.
    AACQ01000062 Genomic DNA. Translation: EAK97854.1.
    PIRiS57923.
    RefSeqiXP_716780.1. XM_711687.1.
    XP_716840.1. XM_711747.1.

    Genome annotation databases

    GeneIDi3641491.
    3641542.
    KEGGical:CaO19.8556.
    cal:CaO19.941.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X81937 Genomic DNA. Translation: CAA57490.1 .
    U61975 mRNA. Translation: AAB41491.1 .
    AACQ01000063 Genomic DNA. Translation: EAK97793.1 .
    AACQ01000062 Genomic DNA. Translation: EAK97854.1 .
    PIRi S57923.
    RefSeqi XP_716780.1. XM_711687.1.
    XP_716840.1. XM_711747.1.

    3D structure databases

    ProteinModelPortali P46250.
    SMRi P46250. Positions 7-296.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0003685.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3641491.
    3641542.
    KEGGi cal:CaO19.8556.
    cal:CaO19.941.

    Organism-specific databases

    CGDi CAL0003685. SEC14.

    Phylogenomic databases

    eggNOGi NOG309458.
    OrthoDBi EOG761C55.

    Family and domain databases

    Gene3Di 3.40.525.10. 1 hit.
    InterProi IPR001071. CRAL-bd_toc_tran.
    IPR001251. CRAL-TRIO_dom.
    IPR011074. CRAL/TRIO_N_dom.
    [Graphical view ]
    Pfami PF00650. CRAL_TRIO. 1 hit.
    PF03765. CRAL_TRIO_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00180. CRETINALDHBP.
    SMARTi SM01100. CRAL_TRIO_N. 1 hit.
    SM00516. SEC14. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46938. SSF46938. 1 hit.
    SSF52087. SSF52087. 1 hit.
    PROSITEi PS50191. CRAL_TRIO. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of Candida albicans SEC14 gene homologue coding for a putative essential function."
      Monteoliva L., Sanchez M., Pla J., Gil C., Nombela C.
      Yeast 12:1097-1105(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 64385 / 1001.
    2. "Two transcripts, differing at their 3' ends, are produced from the Candida albicans SEC14 gene."
      Riggle P.J., Slobodkin I.V., Brown D.H. Jr., Hanson M.P., Volkert T.L., Kumamoto C.A.
      Microbiology 143:3527-3535(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: SGY243.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiSEC14_CANAL
    AccessioniPrimary (citable) accession number: P46250
    Secondary accession number(s): Q5A505
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3