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P46250 (SEC14_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SEC14 cytosolic factor
Alternative name(s):
Phosphatidylinositol/phosphatidylcholine transfer protein
Short name=PI/PC TP
Gene names
Name:SEC14
ORF Names:CaO19.8556, CaO19.941
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length301 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro By similarity.

Subcellular location

Golgi apparatus membrane; Peripheral membrane protein By similarity.

Sequence similarities

Contains 1 CRAL-TRIO domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 301301SEC14 cytosolic factor
PRO_0000210739

Regions

Domain99 – 272174CRAL-TRIO

Sequences

Sequence LengthMass (Da)Tools
P46250 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 1F194A8EA8B525BE

FASTA30134,709
        10         20         30         40         50         60 
MTTMTTEEIL ASYPQITAPT DQTGYTSNLT PEQKTTLDIF RQQLTELGYK DRLDDASLLR 

        70         80         90        100        110        120 
FLRARKFDIQ KAIDMFVACE KWREDFGVNT ILKDFHYEEK PIVAKMYPTY YHKTDKDGRP 

       130        140        150        160        170        180 
VYFEELGKVD LVKMLKITTQ ERMLKNLVWE YEAMCQYRLP ACSRKAGYLV ETSCTVLDLS 

       190        200        210        220        230        240 
GISVTSAYNV IGYVREASKI GQDYYPERMG KFYLINAPFG FSTAFKLFKP FLDPVTVSKI 

       250        260        270        280        290        300 
HILGYSYKKE LLKQIPPQNL PVKFGGMSDV SDDDLLLKDV GPWRDPEFIG PEGECPRAYN 


I 

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References

« Hide 'large scale' references
[1]"Cloning of Candida albicans SEC14 gene homologue coding for a putative essential function."
Monteoliva L., Sanchez M., Pla J., Gil C., Nombela C.
Yeast 12:1097-1105(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 64385 / 1001.
[2]"Two transcripts, differing at their 3' ends, are produced from the Candida albicans SEC14 gene."
Riggle P.J., Slobodkin I.V., Brown D.H. Jr., Hanson M.P., Volkert T.L., Kumamoto C.A.
Microbiology 143:3527-3535(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: SGY243.
[3]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X81937 Genomic DNA. Translation: CAA57490.1.
U61975 mRNA. Translation: AAB41491.1.
AACQ01000063 Genomic DNA. Translation: EAK97793.1.
AACQ01000062 Genomic DNA. Translation: EAK97854.1.
PIRS57923.
RefSeqXP_716780.1. XM_711687.1.
XP_716840.1. XM_711747.1.

3D structure databases

ProteinModelPortalP46250.
SMRP46250. Positions 7-296.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0003685.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3641491.
3641542.
KEGGcal:CaO19.8556.
cal:CaO19.941.

Organism-specific databases

CGDCAL0003685. SEC14.

Phylogenomic databases

eggNOGNOG309458.
OrthoDBEOG761C55.

Family and domain databases

Gene3D3.40.525.10. 1 hit.
InterProIPR001071. CRAL-bd_toc_tran.
IPR001251. CRAL-TRIO_dom.
IPR011074. CRAL/TRIO_N_dom.
[Graphical view]
PfamPF00650. CRAL_TRIO. 1 hit.
PF03765. CRAL_TRIO_N. 1 hit.
[Graphical view]
PRINTSPR00180. CRETINALDHBP.
SMARTSM01100. CRAL_TRIO_N. 1 hit.
SM00516. SEC14. 1 hit.
[Graphical view]
SUPFAMSSF46938. SSF46938. 1 hit.
SSF52087. SSF52087. 1 hit.
PROSITEPS50191. CRAL_TRIO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSEC14_CANAL
AccessionPrimary (citable) accession number: P46250
Secondary accession number(s): Q5A505
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names