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P46240 (AROE_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Shikimate dehydrogenase

EC=1.1.1.25
Gene names
Name:aroE
Ordered Locus Names:BUsg_474
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 273273Shikimate dehydrogenase HAMAP-Rule MF_00222
PRO_0000135996

Regions

Nucleotide binding131 – 1355NADP By similarity

Sites

Active site701Proton acceptor Potential

Experimental info

Sequence conflict203 – 2042LP → T in AAD09433. Ref.1
Sequence conflict2061S → I in AAD09433. Ref.1
Sequence conflict2121T → R in AAD09433. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P46240 [UniParc].

Last modified August 30, 2002. Version 2.
Checksum: 50507AF854774AF6

FASTA27330,885
        10         20         30         40         50         60 
MCKLEKFNYA LFGNPIDHSQ SPKIHNFFAT QTGILHIYKA INIPLDQFSS VVSDFFKKNI 

        70         80         90        100        110        120 
KGANVTAPFK KEAYFFSDKL TERAKIAQSV NTLKKISDKC ILGDNTDGIG LLSDLVRLNF 

       130        140        150        160        170        180 
IKKNFSILIL GAGGAVKGVL LPLLSLGCSV YILNRTILNA KILVKQFNKY GKIFVFDRQN 

       190        200        210        220        230        240 
FKQQNFDLVI NAMSRNTEKK NFLPLSLITS KTFFYDMNYS TRNTPFINWC SKAGGSFISN 

       250        260        270 
GIGMLVFQAA YSFLEWHNVL PEINYIINIL NIK 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of a putative 23S-5S rRNA operon of Buchnera aphidicola (endosymbiont of aphids) unlinked to the 16S rRNA-encoding gene."
Rouhbakhsh D., Baumann P.
Gene 155:107-112(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U09230 Genomic DNA. Translation: AAD09433.1.
AE013218 Genomic DNA. Translation: AAM68017.1.
RefSeqNP_660806.1. NC_004061.1.

3D structure databases

ProteinModelPortalP46240.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg474.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM68017; AAM68017; BUsg_474.
GeneID1005693.
KEGGbas:BUsg474.
PATRIC21247812. VBIBucAph100086_0501.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0169.
KOK00014.
OMADMMYGKE.
OrthoDBEOG6RRKMV.
ProtClustDBPRK00258.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-502-MONOMER.
UniPathwayUPA00053; UER00087.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00222. Shikimate_DH_AroE.
InterProIPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00507. aroE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROE_BUCAP
AccessionPrimary (citable) accession number: P46240
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: August 30, 2002
Last modified: February 19, 2014
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names