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Protein

Triosephosphate isomerase, chloroplastic

Gene
N/A
Organism
Secale cereale (Rye)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

In plants, there are two types of TPIS, cytosolic and plastid.

Catalytic activityi

D-glyceraldehyde 3-phosphate = glycerone phosphate.

Pathwayi: Calvin cycle

This protein is involved in the pathway Calvin cycle, which is part of Carbohydrate biosynthesis.
View all proteins of this organism that are known to be involved in the pathway Calvin cycle and in Carbohydrate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei54SubstrateBy similarity1
Binding sitei56SubstrateBy similarity1
Active sitei138ElectrophileBy similarity1
Active sitei208Proton acceptorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCalvin cycle

Enzyme and pathway databases

UniPathwayiUPA00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Triosephosphate isomerase, chloroplastic (EC:5.3.1.1)
Short name:
TIM
Short name:
Triose-phosphate isomerase
OrganismiSecale cereale (Rye)
Taxonomic identifieri4550 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeSecale

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2366474.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 43Chloroplast1 PublicationAdd BLAST43
ChainiPRO_000003565144 – 298Triosephosphate isomerase, chloroplasticAdd BLAST255

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei186Cysteine derivative1

Proteomic databases

PRIDEiP46225.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP46225.
SMRiP46225.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the triosephosphate isomerase family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

CDDicd00311. TIM. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00147_B. TIM_B. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR035990. TIM_sf.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
PANTHERiPTHR21139. PTHR21139. 1 hit.
PfamiView protein in Pfam
PF00121. TIM. 1 hit.
SUPFAMiSSF51351. SSF51351. 1 hit.
TIGRFAMsiTIGR00419. tim. 1 hit.
PROSITEiView protein in PROSITE
PS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P46225-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARRPSPPP ASPPPPRPRS TTTTRTTSSA SAAPAAAQRL VAMAGSGKFF
60 70 80 90 100
VGGNWKCNGT KESISKLVSD LNAATLESDV DVVVAPPFIY IDQVKSSLTD
110 120 130 140 150
RIEVSAQNTW IGKGGAFTGE ISAEQLVDIG CQWVILGHSE RRHVIGEDDE
160 170 180 190 200
FIGKKAAYAL SQNLKVMACI GELLEEREAG KTFDVCFKQM KAFADNITDW
210 220 230 240 250
TNVVIAYEPV WAIGTGKVAS PEQAQEVHAA VRDWLKTNVS ADVASTVRII
260 270 280 290
YGGSVNAANC AELAKKEDID GFLVGGASLK GPDFATICNS VTSKKVTA
Length:298
Mass (Da):31,633
Last modified:November 1, 1995 - v1
Checksum:iC5B9A42227E5B750
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z32521 mRNA. Translation: CAA83533.1.
PIRiS53761.

Similar proteinsi

Entry informationi

Entry nameiTPIC_SECCE
AccessioniPrimary (citable) accession number: P46225
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families