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P46201

- UTMP_BOVIN

UniProt

P46201 - UTMP_BOVIN

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Protein

Uterine milk protein

Gene
N/A
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei420 – 4212Reactive bond By similarity

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: RefGenome

GO - Biological processi

  1. female pregnancy Source: UniProtKB-KW
  2. negative regulation of endopeptidase activity Source: RefGenome
  3. regulation of proteolysis Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Keywords - Biological processi

Pregnancy

Protein family/group databases

MEROPSiI04.981.

Names & Taxonomyi

Protein namesi
Recommended name:
Uterine milk protein
Short name:
UTMP
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525 Reviewed predictionAdd
BLAST
Chaini26 – 459434Uterine milk proteinPRO_0000032531Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi268 – 2681N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP46201.

Structurei

3D structure databases

ProteinModelPortaliP46201.

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family. UTMP subfamily.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG4826.
HOGENOMiHOG000238521.
HOVERGENiHBG098596.
InParanoidiP46201.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 2 hits.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P46201-1 [UniParc]FASTAAdd to Basket

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MSHGRMNLAL SLVFILCGLF NSIFCEKQQH SQKHMNLVLL KKISALSQKM    50
EAHPKDFAQE LFKALIIEDP RKNIIFSPMA MTTTLATLSL GIKSTMRTHH 100
PEDLKLEPKL LDVHKYLQPL VHVGRELVKQ KVLKHQHILF INRKMMVNQM 150
LLQQISKLQG MDIQMIDFTD IEKAKKTISH HVAEKTHTKI TNLITDLNPE 200
TILCLVNHIF FKGILKRAFQ PKLTQKEVFF VNDQTKVQVD MMRKTERMLY 250
SRSEELHATM VKMPCKGNVS LTLMLPDAGQ FDTDLKKMTA KRAKLQKISD 300
FRLVRLILPK LKISFKINFK HLLPKIDPKH ILTATAISQA ITSKAPLPNL 350
EALHQAEIEL SEHALTVDTA IHTDNLLKVP VKAKEVPAVV KVPMKAKEVP 400
AVVKVPMNTK EVPVVVKVPM NTKEVPVVVK VNRPFLLFVE DEKTQRDLFV 450
GKVLNPQVE 459
Length:459
Mass (Da):52,366
Last modified:November 1, 1995 - v1
Checksum:i4B2EAA6365418244
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22095 mRNA. Translation: AAB61677.1.
RefSeqiNP_777222.1. NM_174797.3.
UniGeneiBt.111575.

Genome annotation databases

GeneIDi286871.
KEGGibta:286871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22095 mRNA. Translation: AAB61677.1 .
RefSeqi NP_777222.1. NM_174797.3.
UniGenei Bt.111575.

3D structure databases

ProteinModelPortali P46201.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I04.981.

Proteomic databases

PRIDEi P46201.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 286871.
KEGGi bta:286871.

Organism-specific databases

CTDi 612383.

Phylogenomic databases

eggNOGi COG4826.
HOGENOMi HOG000238521.
HOVERGENi HBG098596.
InParanoidi P46201.

Miscellaneous databases

NextBioi 20806520.

Family and domain databases

InterProi IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view ]
PANTHERi PTHR11461. PTHR11461. 1 hit.
Pfami PF00079. Serpin. 1 hit.
[Graphical view ]
SMARTi SM00093. SERPIN. 1 hit.
[Graphical view ]
SUPFAMi SSF56574. SSF56574. 2 hits.
PROSITEi PS00284. SERPIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Endometrium.

Entry informationi

Entry nameiUTMP_BOVIN
AccessioniPrimary (citable) accession number: P46201
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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