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Protein

Uterine milk protein

Gene
N/A
Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei420 – 4212Reactive bondBy similarity

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW

GO - Biological processi

  1. female pregnancy Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Keywords - Biological processi

Pregnancy

Protein family/group databases

MEROPSiI04.981.

Names & Taxonomyi

Protein namesi
Recommended name:
Uterine milk protein
Short name:
UTMP
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 459434Uterine milk proteinPRO_0000032531Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi268 – 2681N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiP46201.

Expressioni

Gene expression databases

ExpressionAtlasiP46201. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliP46201.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family. UTMP subfamily.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG4826.
HOGENOMiHOG000238521.
HOVERGENiHBG098596.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 2 hits.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P46201-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHGRMNLAL SLVFILCGLF NSIFCEKQQH SQKHMNLVLL KKISALSQKM
60 70 80 90 100
EAHPKDFAQE LFKALIIEDP RKNIIFSPMA MTTTLATLSL GIKSTMRTHH
110 120 130 140 150
PEDLKLEPKL LDVHKYLQPL VHVGRELVKQ KVLKHQHILF INRKMMVNQM
160 170 180 190 200
LLQQISKLQG MDIQMIDFTD IEKAKKTISH HVAEKTHTKI TNLITDLNPE
210 220 230 240 250
TILCLVNHIF FKGILKRAFQ PKLTQKEVFF VNDQTKVQVD MMRKTERMLY
260 270 280 290 300
SRSEELHATM VKMPCKGNVS LTLMLPDAGQ FDTDLKKMTA KRAKLQKISD
310 320 330 340 350
FRLVRLILPK LKISFKINFK HLLPKIDPKH ILTATAISQA ITSKAPLPNL
360 370 380 390 400
EALHQAEIEL SEHALTVDTA IHTDNLLKVP VKAKEVPAVV KVPMKAKEVP
410 420 430 440 450
AVVKVPMNTK EVPVVVKVPM NTKEVPVVVK VNRPFLLFVE DEKTQRDLFV

GKVLNPQVE
Length:459
Mass (Da):52,366
Last modified:November 1, 1995 - v1
Checksum:i4B2EAA6365418244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22095 mRNA. Translation: AAB61677.1.
RefSeqiNP_777222.1. NM_174797.3.
UniGeneiBt.111575.

Genome annotation databases

GeneIDi286871.
KEGGibta:286871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22095 mRNA. Translation: AAB61677.1.
RefSeqiNP_777222.1. NM_174797.3.
UniGeneiBt.111575.

3D structure databases

ProteinModelPortaliP46201.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI04.981.

Proteomic databases

PRIDEiP46201.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi286871.
KEGGibta:286871.

Organism-specific databases

CTDi612383.

Phylogenomic databases

eggNOGiCOG4826.
HOGENOMiHOG000238521.
HOVERGENiHBG098596.

Miscellaneous databases

NextBioi20806520.

Gene expression databases

ExpressionAtlasiP46201. baseline and differential.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 2 hits.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Endometrium.

Entry informationi

Entry nameiUTMP_BOVIN
AccessioniPrimary (citable) accession number: P46201
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 4, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.