rseC

Functionⁱ

Miscellaneous

Part of the rpoE-rseA-rseB-rseC operon.

GO - Biological processⁱ

response to oxidative stress
Source: EcoCyc
Inferred from mutant phenotypeⁱ
- 24580753

Complete GO annotation...

Enzyme and pathway databases

BioCycⁱ	EcoCyc:G7347-MONOMER.

BioCycⁱ

EcoCyc:G7347-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein RseC
Gene namesⁱ	Name:rseC Ordered Locus Names:b2570, JW2554
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG13178. rseC.

EcoGeneⁱ

EG13178. rseC.

Subcellular locationⁱ

Cell inner membrane; Multi-pass membrane protein

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 79	CytoplasmicSequence analysisAdd BLAST	79
Transmembraneⁱ	80 – 100	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	101 – 121	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	122 – 159	CytoplasmicSequence analysisAdd BLAST	38

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
plasma membrane
Source: EcoCyc
Inferred from direct assayⁱ
- 15919996

Complete GO annotation...

Keywords - Cellular componentⁱ

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechⁱ

Disruption phenotypeⁱ

No effect on sigma-E (rpoE) activity.2 Publications

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000097483	1 – 159	Protein RseCAdd BLAST		159

Proteomic databases

PaxDbⁱ	P46187.
PRIDEⁱ	P46187.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4260599. 11 interactors.
STRINGⁱ	316385.ECDH10B_2738.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P46187.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the RseC family.Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG4105WMJ. Bacteria. COG3086. LUCA.
HOGENOMⁱ	HOG000272284.
InParanoidⁱ	P46187.
KEGG Orthology (KO) More...KOⁱ	K03803.

Family and domain databases

InterProⁱ	View protein in InterPro IPR026268. RseC. IPR007359. SigmaE_reg_RseC_MucC.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04246. RseC_MucC. 1 hit.
PIRSFⁱ	PIRSF004923. RseC. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

P46187-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MIKEWATVVS WQNGQALVSC DVKASCSSCA SRAGCGSRVL NKLGPQTTHT 
        60         70         80         90        100
IVVPCDEPLV PGQKVELGIA EGSLLSSALL VYMSPLVGLF LIASLFQLLF 
       110        120        130        140        150
ASDVAALCGA ILGGIGGFLI ARGYSRKFAA RAEWQPIILS VALPPGLVRF 

ETSSEDASQ

Length:159

Mass (Da):16,639

Last modified:November 1, 1995 - v1

Checksum:ⁱBCFD8970DF6277C0

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U37089 Genomic DNA. Translation: AAC45317.1. U37455 Genomic DNA. Translation: AAC45320.1. D64044 Genomic DNA. Translation: BAA10917.1. U00096 Genomic DNA. Translation: AAC75623.1. AP009048 Genomic DNA. Translation: BAE76746.1.
PIRⁱ	I83299.
NCBI Reference Sequences More...RefSeqⁱ	NP_417065.1. NC_000913.3. WP_000589068.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAC75623; AAC75623; b2570. BAE76746; BAE76746; BAE76746.
GeneIDⁱ	947052.
KEGGⁱ	ecj:JW2554. eco:b2570.
PATRICⁱ	fig\|1411691.4.peg.4164.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U37089 Genomic DNA. Translation: AAC45317.1. U37455 Genomic DNA. Translation: AAC45320.1. D64044 Genomic DNA. Translation: BAA10917.1. U00096 Genomic DNA. Translation: AAC75623.1. AP009048 Genomic DNA. Translation: BAE76746.1.
PIRⁱ	I83299.
NCBI Reference Sequences More...RefSeqⁱ	NP_417065.1. NC_000913.3. WP_000589068.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortalⁱ	P46187.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4260599. 11 interactors.
STRINGⁱ	316385.ECDH10B_2738.

Proteomic databases

PaxDbⁱ	P46187.
PRIDEⁱ	P46187.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC75623; AAC75623; b2570. BAE76746; BAE76746; BAE76746.
GeneIDⁱ	947052.
KEGGⁱ	ecj:JW2554. eco:b2570.
PATRICⁱ	fig\|1411691.4.peg.4164.

Organism-specific databases

EchoBASEⁱ	EB2970.
EcoGeneⁱ	EG13178. rseC.

Phylogenomic databases

eggNOGⁱ	ENOG4105WMJ. Bacteria. COG3086. LUCA.
HOGENOMⁱ	HOG000272284.
InParanoidⁱ	P46187.
KEGG Orthology (KO) More...KOⁱ	K03803.

Enzyme and pathway databases

BioCycⁱ	EcoCyc:G7347-MONOMER.

BioCycⁱ

EcoCyc:G7347-MONOMER.

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P46187.

PROⁱ

PR:P46187.

Family and domain databases

InterProⁱ	View protein in InterPro IPR026268. RseC. IPR007359. SigmaE_reg_RseC_MucC.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04246. RseC_MucC. 1 hit.
PIRSFⁱ	PIRSF004923. RseC. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RSEC_ECOLI
Accessionⁱ	P46187Primary (citable) accession number: P46187 Secondary accession number(s): Q2MAG0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
	Last sequence update:	November 1, 1995
	Last modified:	July 5, 2017
	This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Caution

Was originally suggested to positively regulate sigma-E activity in vitro.1 Publication

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P46187 (RSEC_ECOLI)

Your basket is currently empty.

Protein RseC

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Documents

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ