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P46148 (ETRA_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Electron transport regulator A
Gene names
Name:etrA
Ordered Locus Names:SO_2356
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Regulates anaerobic growth on fumarate, nitrite, Fe3+, TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn4+.

Subunit structure

Monomer By similarity.

Miscellaneous

Possesses 4 cysteines which may bind a metal ion (possibly iron).

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 250250Electron transport regulator A
PRO_0000100155

Regions

Domain164 – 23774HTH crp-type
DNA binding197 – 21620H-T-H motif Potential

Experimental info

Sequence conflict301I → M in AAA71987. Ref.1
Sequence conflict641P → L in AAA71987. Ref.1
Sequence conflict721R → P in AAA71987. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P46148 [UniParc].

Last modified November 25, 2002. Version 2.
Checksum: 24C82E3C8C3E5743

FASTA25027,889
        10         20         30         40         50         60 
MTIEQNKNRR SAASGCAIHC HDCSMGTLCI PFTLNANELD QLDDIIERKK PIQKGEQIFK 

        70         80         90        100        110        120 
SGDPLKSLFA IRSGTIKSYT ITEQGDEQIT GFHLAGDVIG FDGIHAQSHQ SFAQALETSM 

       130        140        150        160        170        180 
VCEIPFNILD ELSGTMPKLR QQIMRLMSNE IMSDQEMILL LSKKNAEERL AAFISNLANR 

       190        200        210        220        230        240 
FGNRGFSAKE FRLTMTRGDI GNYLGLTVET ISRLLGRFQK SGLIEVKGKY IIIVDHHELN 

       250 
LLAGNARIAR 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and genetic characterization of etrA, an fnr analog that regulates anaerobic respiration in Shewanella putrefaciens MR-1."
Saffarini D.A., Nealson K.H.
J. Bacteriol. 175:7938-7944(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: MR-1.
[2]"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis."
Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T. expand/collapse author list , Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.
Nat. Biotechnol. 20:1118-1123(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MR-1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L13868 Unassigned DNA. Translation: AAA71987.1.
AE014299 Genomic DNA. Translation: AAN55390.2.
PIRA49910.
RefSeqNP_717946.2. NC_004347.2.

3D structure databases

ProteinModelPortalP46148.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_2356.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN55390; AAN55390; SO_2356.
GeneID1170077.
KEGGson:SO_2356.
PATRIC23524333. VBISheOne101494_2267.

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000186461.
KOK01420.
OMAFSANQFR.
OrthoDBEOG6RVFWF.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSPR00034. HTHCRP.
SMARTSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameETRA_SHEON
AccessionPrimary (citable) accession number: P46148
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 25, 2002
Last modified: May 14, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families