Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P46148

- ETRA_SHEON

UniProt

P46148 - ETRA_SHEON

Protein

Electron transport regulator A

Gene

etrA

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 2 (25 Nov 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Regulates anaerobic growth on fumarate, nitrite, Fe3+, TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn4+.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi197 – 21620H-T-H motifPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: TIGR

    GO - Biological processi

    1. anaerobic respiration Source: TIGR
    2. regulation of transcription, DNA-templated Source: TIGR
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Electron transport regulator A
    Gene namesi
    Name:etrA
    Ordered Locus Names:SO_2356
    OrganismiShewanella oneidensis (strain MR-1)
    Taxonomic identifieri211586 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000008186: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 250250Electron transport regulator APRO_0000100155Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi211586.SO_2356.

    Structurei

    3D structure databases

    ProteinModelPortaliP46148.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini164 – 23774HTH crp-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 cyclic nucleotide-binding domain.PROSITE-ProRule annotation
    Contains 1 HTH crp-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0664.
    HOGENOMiHOG000186461.
    KOiK01420.
    OMAiFSANQFR.
    OrthoDBiEOG6RVFWF.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    2.60.120.10. 1 hit.
    InterProiIPR018490. cNMP-bd-like.
    IPR000595. cNMP-bd_dom.
    IPR012318. HTH_CRP_2.
    IPR014710. RmlC-like_jellyroll.
    IPR001808. Tscrpt_reg_HTH_Crp.
    IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00027. cNMP_binding. 1 hit.
    PF00325. Crp. 1 hit.
    [Graphical view]
    PRINTSiPR00034. HTHCRP.
    SMARTiSM00100. cNMP. 1 hit.
    SM00419. HTH_CRP. 1 hit.
    [Graphical view]
    SUPFAMiSSF51206. SSF51206. 1 hit.
    PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
    PS00042. HTH_CRP_1. 1 hit.
    PS51063. HTH_CRP_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P46148-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTIEQNKNRR SAASGCAIHC HDCSMGTLCI PFTLNANELD QLDDIIERKK    50
    PIQKGEQIFK SGDPLKSLFA IRSGTIKSYT ITEQGDEQIT GFHLAGDVIG 100
    FDGIHAQSHQ SFAQALETSM VCEIPFNILD ELSGTMPKLR QQIMRLMSNE 150
    IMSDQEMILL LSKKNAEERL AAFISNLANR FGNRGFSAKE FRLTMTRGDI 200
    GNYLGLTVET ISRLLGRFQK SGLIEVKGKY IIIVDHHELN LLAGNARIAR 250
    Length:250
    Mass (Da):27,889
    Last modified:November 25, 2002 - v2
    Checksum:i24C82E3C8C3E5743
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti30 – 301I → M in AAA71987. (PubMed:8253682)Curated
    Sequence conflicti64 – 641P → L in AAA71987. (PubMed:8253682)Curated
    Sequence conflicti72 – 721R → P in AAA71987. (PubMed:8253682)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13868 Unassigned DNA. Translation: AAA71987.1.
    AE014299 Genomic DNA. Translation: AAN55390.2.
    PIRiA49910.
    RefSeqiNP_717946.2. NC_004347.2.

    Genome annotation databases

    EnsemblBacteriaiAAN55390; AAN55390; SO_2356.
    GeneIDi1170077.
    KEGGison:SO_2356.
    PATRICi23524333. VBISheOne101494_2267.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13868 Unassigned DNA. Translation: AAA71987.1 .
    AE014299 Genomic DNA. Translation: AAN55390.2 .
    PIRi A49910.
    RefSeqi NP_717946.2. NC_004347.2.

    3D structure databases

    ProteinModelPortali P46148.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 211586.SO_2356.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN55390 ; AAN55390 ; SO_2356 .
    GeneIDi 1170077.
    KEGGi son:SO_2356.
    PATRICi 23524333. VBISheOne101494_2267.

    Phylogenomic databases

    eggNOGi COG0664.
    HOGENOMi HOG000186461.
    KOi K01420.
    OMAi FSANQFR.
    OrthoDBi EOG6RVFWF.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    2.60.120.10. 1 hit.
    InterProi IPR018490. cNMP-bd-like.
    IPR000595. cNMP-bd_dom.
    IPR012318. HTH_CRP_2.
    IPR014710. RmlC-like_jellyroll.
    IPR001808. Tscrpt_reg_HTH_Crp.
    IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00027. cNMP_binding. 1 hit.
    PF00325. Crp. 1 hit.
    [Graphical view ]
    PRINTSi PR00034. HTHCRP.
    SMARTi SM00100. cNMP. 1 hit.
    SM00419. HTH_CRP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51206. SSF51206. 1 hit.
    PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
    PS00042. HTH_CRP_1. 1 hit.
    PS51063. HTH_CRP_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and genetic characterization of etrA, an fnr analog that regulates anaerobic respiration in Shewanella putrefaciens MR-1."
      Saffarini D.A., Nealson K.H.
      J. Bacteriol. 175:7938-7944(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: MR-1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MR-1.

    Entry informationi

    Entry nameiETRA_SHEON
    AccessioniPrimary (citable) accession number: P46148
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 25, 2002
    Last modified: October 1, 2014
    This is version 98 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Possesses 4 cysteines which may bind a metal ion (possibly iron).

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3