Reviewed,
UniProtKB/Swiss-Prot P46133 (ABGT_ECOLI)
Last modified
November 24, 2009.
Version 78.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Aminobenzoyl-glutamate transport protein | ||||||||
| Gene names |
| ||||||||
| Organism | Escherichia coli (strain K12) [Complete proteome] [HAMAP] | ||||||||
| Taxonomic identifier | 83333 [NCBI] | ||||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 508 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Essential for aminobenzoyl-glutamate utilization. May transport aminobenzoyl-glutamate into the cell. Seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate. Sufficient to confer aminobenzoyl-glutamate utilization phenotype. |
| Subcellular location | |
| Miscellaneous | It is suggested that in wild-type strain abgT would normally be cryptic or not expressed under conditions of growth on minimal medium. Altering the expression of abgT from its wild-type context appears to be the mechanism for obtaining the growth phenotype. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid transport Transport |
| Cellular component | Cell inner membrane Cell membrane Membrane |
| Domain | Transmembrane |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | amino acid transport Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 508 | 508 | Aminobenzoyl-glutamate transport protein | PRO_0000064422 | |||||
Regions | |||||||||
| Transmembrane | 30 – 50 | 21 | Potential | ||||||
| Transmembrane | 85 – 105 | 21 | Potential | ||||||
| Transmembrane | 121 – 139 | 19 | Potential | ||||||
| Transmembrane | 140 – 159 | 20 | Potential | ||||||
| Transmembrane | 164 – 184 | 21 | Potential | ||||||
| Transmembrane | 211 – 231 | 21 | Potential | ||||||
| Transmembrane | 261 – 281 | 21 | Potential | ||||||
| Transmembrane | 303 – 323 | 21 | Potential | ||||||
| Transmembrane | 343 – 363 | 21 | Potential | ||||||
| Transmembrane | 382 – 402 | 21 | Potential | ||||||
| Transmembrane | 405 – 425 | 21 | Potential | ||||||
| Transmembrane | 439 – 459 | 21 | Potential | ||||||
| Transmembrane | 479 – 499 | 21 | Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 504 | 1 | Y → S Ref.2 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Characterization of mutations that allow p-aminobenzoyl-glutamate utilization by Escherichia coli." Hussein M.J., Green J.M., Nichols B.P. J. Bacteriol. 180:6260-6268(1998) [PubMed: 9829935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION. Strain: BN1001 and BN1003. |
| [2] | "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. Horiuchi T.DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911. |
| [3] | "The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076. |
| [4] | "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 504. Strain: K12 / W3110 / ATCC 27325 / DSM 5911. |
| [5] | "Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli." Potter P.M., Wilkinson M.C., Fitton J., Carr F.J., Brennand J., Cooper D.P., Margison G.P. Nucleic Acids Res. 15:9177-9193(1987) [PubMed: 2825131] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 452-508. |
| [6] | "Detection of new genes in a bacterial genome using Markov models for three gene classes." Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A. Nucleic Acids Res. 23:3554-3562(1995) [PubMed: 7567469] [Abstract] Cited for: IDENTIFICATION. |
| [7] | "Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed: 15919996] [Abstract] Cited for: SUBCELLULAR LOCATION. Strain: K12 / MG1655 / ATCC 47076. |
Cross-references
Sequence databases | |
|---|---|
| U00096 Genomic DNA. Translation: AAC74418.2. AP009048 Genomic DNA. Translation: BAA14929.2. Y00495 Genomic DNA. No translation available. | |
| PIR | C64883. |
| RefSeq | AP_001964.1. NP_415852.2. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:9031N. |
| STRING | P46133. |
Protein family/group databases | |
| TCDB | 2.A.68.1.1. p-aminobenzoyl-glutamate transporter (AbgT) family. |
Genome annotation databases | |
| GeneID | 945912. |
| GenomeReviews | Gene locus JW5822 in contig AP009048_GR. Gene locus b1336 in contig U00096_GR. |
| KEGG | ecj:JW5822. eco:b1336. |
Organism-specific databases | |
| EchoBASE | EB2697. |
| EcoGene | EG12853. abgT. |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P46133. |
| OMA | KWSDKFL |
Enzyme and pathway databases | |
| BioCyc | EcoCyc:ABGT-MON. ECOL168927:B1336-MON. |
Gene expression databases | |
| Genevestigator | P46133. |
Family and domain databases | |
| InterPro | IPR004697. Put_transpt_AbgT. IPR011540. YdaH_transpt. [Graphical view] |
| Pfam | PF03806. ABG_transport. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00819. ydaH. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ABGT_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P46133 Secondary accession number(s): P76051, P76843, P76845 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |

Clusters with


