Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 66  Show
  1. 1
    "Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization."
    Liang R., Fei Y.-J., Prasad P.D., Ramamoorthy S., Han H., Yang-Feng T.L., Hediger M.A., Ganapathy V., Leibach F.H.
    J. Biol. Chem. 270:6456-6463(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Tissue: Intestine.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 806 other entries.

  3. 3
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50494 other entries.

  4. 4
    "Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population."
    Saito S., Iida A., Sekine A., Ogawa C., Kawauchi S., Higuchi S., Nakamura Y.
    J. Hum. Genet. 47:576-584(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS ASN-117 AND ALA-419.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  5. 5
    Cited for: VARIANTS ILE-21; TYR-28; ASN-117; ARG-117; MET-122; ALA-419; ILE-450; ASN-451 AND SER-537.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Thyroid hormone regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells."
    Ashida K., Katsura T., Motohashi H., Saito H., Inui K.
    Am. J. Physiol. Gastrointest. Liver Physiol. 282:G617-23(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: 3 5 3'-L-triiodothyronine regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  7. 7
    "Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function."
    Doring F., Martini C., Walter J., Daniel H.
    J. Membr. Biol. 186:55-62(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: the two identified aminoterminal regions in mammalian peptide carriers play an important role in determining the substrate affinity and also other characteristic features of the two transporter subtypes.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 10 other entries.

  8. 8
    "Hormonal regulation of dipeptide transporter (PepT1) in Caco-2 cells with normal and anoxia/reoxygenation management."
    Sun B.W., Zhao X.C., Wang G.J., Li N., Li J.S.
    World J. Gastroenterol. 9:808-812(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: Hormonal regulation of this transporter in Caco-2 cells with normal and anoxia/reoxygenation management.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  9. 9
    "Transmembrane segment 5 of the dipeptide transporter hPepT1 forms a part of the substrate translocation pathway."
    Kulkarni A.A., Haworth I.S., Lee V.H.
    Biochem. Biophys. Res. Commun. 306:177-185(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: role of transmembrane segment 5 of hPepT1 the most conserved segment across different species in forming a part of the aqueous substrate translocation pathwayImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  10. 10
    "Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis."
    Kulkarni A.A., Haworth I.S., Uchiyama T., Lee V.H.
    J. Biol. Chem. 278:51833-51840(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: the extracellular end of TMS7 may shift following substrate binding providing the basis for channel opening and substrate translocationImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  11. 11
    "Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease."
    Adibi S.A.
    Am. J. Physiol. Gastrointest. Liver Physiol. 285:G779-88(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: Wealth of new information on regulation of key transporter in intestine. Useful applications in nutritional and pharmacological treatments. Review.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  12. 12
    "Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1."
    Uchiyama T., Kulkarni A.A., Davies D.L., Lee V.H.
    Pharm. Res. 20:1911-1916(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: hPepT1 is able to bind protons at a relatively basic pH resulting in facilitation of transport of Gly-Sar by hPepT1 at higher pHImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  13. 13
    "hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells."
    Vavricka S.R., Musch M.W., Chang J.E., Nakagawa Y., Phanvijhitsiri K., Waypa T.S., Merlin D., Schneewind O., Chang E.B.
    Gastroenterology 127:1401-1409(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: hPepT1 expression in colonic inflammation is increased which plays an important role in promoting participation in host defense.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 7 other entries.

  14. 14
    "Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells."
    Alteheld B., Evans M.E., Gu L.H., Ganapathy V., Leibach F.H., Jones D.P., Ziegler T.R.
    J. Nutr. 135:19-26(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Ala-Gln but not somatropin maintained cellular glutathione and prevented the decrease in PepT1 protein expression.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  15. 15
    "Computational modelling of H+-coupled peptide transport via human PEPT1."
    Irie M., Terada T., Katsura T., Matsuoka S., Inui K.
    J. Physiol. (Lond.) 565:429-439(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: the inferred mechanisms are able to sufficiently interpret the transport of both neutral and charged substrates by PEPT1Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  16. 16
    "A novel high-throughput pepT1 transporter assay differentiates between substrates and antagonists."
    Faria T.N., Timoszyk J.K., Stouch T.R., Vig B.S., Landowski C.P., Amidon G.L., Weaver C.D., Wall D.A., Smith R.L.
    Mol. Pharm. 1:67-76(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: PepT1 is a transporter of proven pharmaceutical utility for enhancing oral absorption.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  17. 17
    "A novel hPepT1 stably transfected cell line: establishing a correlation between expression and function."
    Herrera-Ruiz D., Faria T.N., Bhardwaj R.K., Timoszyk J., Gudmundsson O.S., Moench P., Wall D.A., Smith R.L., Knipp G.T.
    Mol. Pharm. 1:136-144(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Transfected hPepT1 cell line may serve as a useful in vitro model for screening and quantifying peptide and peptide-like drug transportImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  18. 18
    "Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1."
    Biegel A., Gebauer S., Hartrodt B., Brandsch M., Neubert K., Thondorf I.
    J. Med. Chem. 48:4410-4419(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Identification of regions which are crucial for the interaction between peptidomimetics and PEPT1.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  19. 19
    "Comparison of human and monkey peptide transporters: PEPT1 and PEPT2."
    Zhang E.Y., Emerick R.M., Pak Y.A., Wrighton S.A., Hillgren K.M.
    Mol. Pharm. 1:201-210(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: functionalities of PEPT1 and PEPT2 were largely conserved in terms of glycylsarcosine uptake kinetics and inhibitor specificityImported.
    Source: GeneRIF:6564.

    This publication is mapped to 10 other entries.

  20. 20
    "Possible role of PEPT1 in gastrointestinal hormone secretion."
    Matsumura K., Miki T., Jhomori T., Gonoi T., Seino S.
    Biochem. Biophys. Res. Commun. 336:1028-1032(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: PEPT1 mediates oligopeptide-induced hormone secretion in enteroendocrine cells.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  21. 21
    "Recovery of functional peptide transporter PepT1 in budded baculovirus fraction."
    Saitoh R., Ohtomo T., Ito Y., Nezu J., Kimura N., Funahashi S., Aso Y., Ohizumi I., Kodama T., Hamakubo T., Tsuchiya M.
    Protein Expr. Purif. 46:130-135(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: Functional PepT1 recovers efficiently in a budded virus fraction and this expression system will be a useful tool for characterization and screening of peptide-mimetic drugs in drug discovery.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  22. 22
    "Regulation of human peptide transporter 1 (PEPT1) in gastric cancer cells by anticancer drugs."
    Inoue M., Terada T., Okuda M., Inui K.
    Cancer Lett. 230:72-80(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: PEPT1 is expressed and functional in MKN45 cells; function of PEPT1 is unaffected by cellular injury induced by fluorouracilImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  23. 23
    "Prediction of glycylsarcosine transport in Caco-2 cell lines expressing PEPT1 at different levels."
    Irie M., Terada T., Tsuda M., Katsura T., Inui K.
    Pflugers Arch. 452:64-70(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: model can simulate Gly-Sar transport in cells expressing PEPT1 at different levelsImported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

  24. 24
    "Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine."
    Vavricka S.R., Musch M.W., Fujiya M., Kles K., Chang L., Eloranta J.J., Kullak-Ublick G.A., Drabik K., Merlin D., Chang E.B.
    Pflugers Arch. 452:71-80(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: Tumor necrosis factor-alpha and interferon-gamma increased the expression of PepT1 protein in a concentration- and time-dependent fashion.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 8 other entries.

  25. 25
    "hPepT1 mediates bacterial tripeptide fMLP uptake in human monocytes."
    Charrier L., Driss A., Yan Y., Nduati V., Klapproth J.M., Sitaraman S.V., Merlin D.
    Lab. Invest. 86:490-503(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: hPepT1 is expressed in macrophages where the transporter functions best at the physiological pH 7.2. hPepT1-mediates fMLP transport which might constitute a novel immune cell activation pathway during intestinal inflammation.Imported.
    Source: GeneRIF:6564.

    This publication is mapped to 5 other entries.

1 to 25 of 66  Show