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P46016

- 6PGL_NOSS1

UniProt

P46016 - 6PGL_NOSS1

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 2 (23 Jan 2002)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

    GO - Biological processi

    1. heterocyst differentiation Source: UniProtKB-KW
    2. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    Name:pgl
    Synonyms:devB
    Ordered Locus Names:alr1602
    OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
    Taxonomic identifieri103690 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
    ProteomesiUP000002483: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2402406-phosphogluconolactonasePRO_0000090087Add
    BLAST

    Expressioni

    Developmental stagei

    Developmentally regulated gene in heterocyst development.

    Keywords - Developmental stagei

    Heterocyst

    Interactioni

    Protein-protein interaction databases

    STRINGi103690.alr1602.

    Structurei

    3D structure databases

    ProteinModelPortaliP46016.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    HOGENOMiHOG000256282.
    KOiK01057.
    OMAiERVCAWE.
    OrthoDBiEOG63FW46.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P46016-1 [UniParc]FASTAAdd to Basket

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    MKKTVEVLPD QTALIARSLD LILTKLDTAI KQQGRFTIAL SGGSTPKPLY    50
    EAIAAQKLPW DKIHVFWGDE RYVSPDHPDS NELMARTAWL DRVDIPAENI 100
    HAVPTLDNNP AVSAAKYEQH LQTFFNSAPG EFPALDVVLL GMGDDAHTAS 150
    LFPHTEALQV RDRLITVGNK DGNPRITFTY PFINAASSVI FVVAGANKRP 200
    ALAQVFAPSA DDLAYPSRFI QPQGELLWLL DAAAGAELSV 240
    Length:240
    Mass (Da):26,183
    Last modified:January 23, 2002 - v2
    Checksum:i69DA7B9A72729F96
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti13 – 164ALIA → RSI in AAA50355. 1 PublicationCurated
    Sequence conflicti99 – 991N → D in AAA50355. 1 PublicationCurated
    Sequence conflicti235 – 2373GAE → RRT in AAA50355. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U14553 Genomic DNA. Translation: AAA50355.1.
    BA000019 Genomic DNA. Translation: BAB77968.1.
    PIRiAD2006.
    RefSeqiNP_485642.1. NC_003272.1.
    WP_010995771.1. NC_003272.1.

    Genome annotation databases

    EnsemblBacteriaiBAB77968; BAB77968; BAB77968.
    GeneIDi1105194.
    KEGGiana:alr1602.
    PATRICi22773236. VBINosSp37423_2098.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U14553 Genomic DNA. Translation: AAA50355.1 .
    BA000019 Genomic DNA. Translation: BAB77968.1 .
    PIRi AD2006.
    RefSeqi NP_485642.1. NC_003272.1.
    WP_010995771.1. NC_003272.1.

    3D structure databases

    ProteinModelPortali P46016.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 103690.alr1602.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB77968 ; BAB77968 ; BAB77968 .
    GeneIDi 1105194.
    KEGGi ana:alr1602.
    PATRICi 22773236. VBINosSp37423_2098.

    Phylogenomic databases

    eggNOGi COG0363.
    HOGENOMi HOG000256282.
    KOi K01057.
    OMAi ERVCAWE.
    OrthoDBi EOG63FW46.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Bacterial subtracted cDNA libraries containing genes involved in the differentiation of vegetative cells to heterocysts allow a new twist on an old method of isolating developmental genes."
      Bauer C.C., Scappino L., Haselkorn R.
      Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 7120 / UTEX 2576.

    Entry informationi

    Entry namei6PGL_NOSS1
    AccessioniPrimary (citable) accession number: P46016
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: January 23, 2002
    Last modified: October 1, 2014
    This is version 82 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3