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P46016

- 6PGL_NOSS1

UniProt

P46016 - 6PGL_NOSS1

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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. heterocyst differentiation Source: UniProtKB-KW
  2. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:alr1602
OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
ProteomesiUP000002483: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2402406-phosphogluconolactonasePRO_0000090087Add
BLAST

Expressioni

Developmental stagei

Developmentally regulated gene in heterocyst development.

Keywords - Developmental stagei

Heterocyst

Interactioni

Protein-protein interaction databases

STRINGi103690.alr1602.

Structurei

3D structure databases

ProteinModelPortaliP46016.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256282.
KOiK01057.
OMAiERVCAWE.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

P46016-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKTVEVLPD QTALIARSLD LILTKLDTAI KQQGRFTIAL SGGSTPKPLY
60 70 80 90 100
EAIAAQKLPW DKIHVFWGDE RYVSPDHPDS NELMARTAWL DRVDIPAENI
110 120 130 140 150
HAVPTLDNNP AVSAAKYEQH LQTFFNSAPG EFPALDVVLL GMGDDAHTAS
160 170 180 190 200
LFPHTEALQV RDRLITVGNK DGNPRITFTY PFINAASSVI FVVAGANKRP
210 220 230 240
ALAQVFAPSA DDLAYPSRFI QPQGELLWLL DAAAGAELSV
Length:240
Mass (Da):26,183
Last modified:January 23, 2002 - v2
Checksum:i69DA7B9A72729F96
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti13 – 164ALIA → RSI in AAA50355. 1 PublicationCurated
Sequence conflicti99 – 991N → D in AAA50355. 1 PublicationCurated
Sequence conflicti235 – 2373GAE → RRT in AAA50355. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U14553 Genomic DNA. Translation: AAA50355.1.
BA000019 Genomic DNA. Translation: BAB77968.1.
PIRiAD2006.
RefSeqiNP_485642.1. NC_003272.1.
WP_010995771.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB77968; BAB77968; BAB77968.
GeneIDi1105194.
KEGGiana:alr1602.
PATRICi22773236. VBINosSp37423_2098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U14553 Genomic DNA. Translation: AAA50355.1 .
BA000019 Genomic DNA. Translation: BAB77968.1 .
PIRi AD2006.
RefSeqi NP_485642.1. NC_003272.1.
WP_010995771.1. NC_003272.1.

3D structure databases

ProteinModelPortali P46016.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 103690.alr1602.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB77968 ; BAB77968 ; BAB77968 .
GeneIDi 1105194.
KEGGi ana:alr1602.
PATRICi 22773236. VBINosSp37423_2098.

Phylogenomic databases

eggNOGi COG0363.
HOGENOMi HOG000256282.
KOi K01057.
OMAi ERVCAWE.
OrthoDBi EOG63FW46.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Bacterial subtracted cDNA libraries containing genes involved in the differentiation of vegetative cells to heterocysts allow a new twist on an old method of isolating developmental genes."
    Bauer C.C., Scappino L., Haselkorn R.
    Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7120 / UTEX 2576.

Entry informationi

Entry namei6PGL_NOSS1
AccessioniPrimary (citable) accession number: P46016
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2002
Last modified: October 1, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3