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Reviewed, UniProtKB/Swiss-Prot P45890 (ARP6_DROME)

Last modified November 24, 2009. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Actin-like protein 13E
Alternative name(s):
    Actin-related protein 6
    dArp6
Gene names
Name: Actr13E
Synonyms: Acrp
ORF Names: CG11678
OrganismDrosophila melanogaster (Fruit fly) [Complete proteome]
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

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Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Nucleus. Cytoplasm › cytoskeleton. Note: Localized on centric heterochromatin.

Sequence similarities

Belongs to the actin family. ARP6 subfamily.

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Ontologies

Keywords
   Cellular componentCytoplasm
Cytoskeleton
Nucleus
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-KW

cytoskeleton

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

Q9VDN61EBI-163314,EBI-190951

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Actin-like protein 13E
PRO_0000089108

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Sequences

Sequence LengthMass (Da)Tools
P45890-1 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 71905627B3F0FC05

FASTA39845,415
        10         20         30         40         50         60 
MANAVVVLDN GAHTAKVGLA NQDEPHVVPN CIMKAKSERR RAFVGNQIDE CRDTSALYYI 

        70         80         90        100        110        120 
LAFQRGYLLN WHTQKTVWDY IFSKDGIGCS LENRNIVITE PQMNFQSIQE ATLEILFEEY 

       130        140        150        160        170        180 
KVDGVYKTTA ADLAAFNYVA DSEERTTMES LNCIIIDVGY SFTHVVPFVL GRRVLQGIRR 

       190        200        210        220        230        240 
IDMGGKALTN QLKELISYRH LNVMDESHVV NQIKEDVCFV AEDFKQAMQV HYSEEKRREV 

       250        260        270        280        290        300 
TVDYVLPDFT TVKRGYVRVP GKPREDEEQQ QMVSLCNERF TVPELLFNPS DIGVQQVGIP 

       310        320        330        340        350        360 
EAVADCLKAC PWEAHRELLL NILIVGGSAQ FPGFLPRLKR DLRALVPDDL EVSLICPEDP 

       370        380        390 
VRYAWYGGKE VATSPNFEEF VYTQDDYEEY GFQGINQR

« Hide

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References

« Hide 'large scale' references
[1]"Identification of a divergent actin-related protein in Drosophila."
Frankel S., Heintzelman M.B., Artavanis-Tsakonas S., Mooseker M.S.
J. Mol. Biol. 235:1351-1356(1994) [PubMed: 8308899] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Canton-S.
[2]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[3]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: GENOME REANNOTATION.
[4]"A Drosophila full-length cDNA resource."
Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E.
Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Berkeley.
Tissue: Embryo.
+Additional computationally mapped references.

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Cross-references

Sequence databases

L25314 mRNA. Translation: AAA17685.1.
AE014298 Genomic DNA. Translation: AAF48499.1.
AY058726 mRNA. Translation: AAL13955.1.
PIRS44028.
RefSeqNP_511165.1.
UniGeneDm.19111

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:17460N.
IntActP45890. 27 interactions.
STRINGP45890.

Proteomic databases

PRIDEP45890.

Genome annotation databases

EnsemblFBtr0074203; FBpp0073983; FBgn0011741; Drosophila melanogaster. [Genome view]
GeneID32514.
KEGGdme:Dmel_CG11678.
NMPDRfig|7227.3.peg.17988.

Organism-specific databases

CTD32514.
FlyBaseFBgn0011741. Actr13E.

Phylogenomic databases

HOGENOMP45890.
OMAFPGFRER
OrthoDBEOG96T37F

Enzyme and pathway databases

BioCycDMEL-XXX-02:DMEL-XXX-02-002028-MON.

Gene expression databases

BgeeP45890.
GermOnlineCG11678. Drosophila melanogaster.

Family and domain databases

InterProIPR004000. Actin-like.
[Graphical view]
PANTHERPTHR11937. Actin_like. 1 hit.
PfamPF00022. Actin. 1 hit.
[Graphical view]
SMARTSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio778857.

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Entry information

Entry nameARP6_DROME
AccessionPrimary (citable) accession number: P45890
Secondary accession number(s): Q9VXQ9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 24, 2009
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectDrosophila annotation project

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Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents