Acyl-CoA dehydrogenase - Bacillus subtilis

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P45857 (ACDB_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 88. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Acyl-CoA dehydrogenase
EC=1.3.99.-

Gene names

Name:	mmgC
Synonyms:	yqiN
Ordered Locus Names:	BSU24150

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
Cofactor	FAD By similarity.
Developmental stage	Expressed in the mother cell at intermediate stages of sporulation under the control of the sigma-E factor. Ref.1
Induction	Subject to catabolite repression. Ref.1
Sequence similarities	Belongs to the acyl-CoA dehydrogenase family.

Ontologies

Keywords
Biological process	Sporulation
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	acyl-CoA dehydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 379

379

Acyl-CoA dehydrogenase

PRO_0000201183

Experimental info

Sequence conflict

L → M in AAB09615. Ref.1

Sequence conflict

171

A → D in AAB09615. Ref.1

Sequence conflict

329

Missing in BAA12589. Ref.2

Sequences

Sequence

Length

Mass (Da)

Tools

P45857 [UniParc].

Last modified July 7, 2009. Version 3.
Checksum: 842FA980747D6C20
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FASTA

379

40,941

        10         20         30         40         50         60 
MHVTQEQVMM RKMVRDFARK EIAPAAEIME KTDEFPFQLI KKMGKHGLMG IPVPEQYGGA 

        70         80         90        100        110        120 
GADVVSYILA IHEISRISAA VGVILSVHTS VGTNPILYFG NEEQKMKYIP NLASGDHLGA 

       130        140        150        160        170        180 
FALTEPHSGS DAGSLRTTAI KKNGKYLLNG SKIFITNGGA ADIYITFALT APDQGRHGIS 

       190        200        210        220        230        240 
AFIVEKNTPG FTVGKKERKL GLYGSNTTEL IFDNAEVPEA NLLGKEGDGF HIAMANLNVG 

       250        260        270        280        290        300 
RIGIAAQALG IAEAALEHAV DYAKQRVQFG RPIAANQGIS FKLADMATRA EAARHLVYHA 

       310        320        330        340        350        360 
ADLHNRGLNC GKEASMAKQF ASDAAVKAAL DAVQIYGGYG YMKDYPVERL LRDAKVTQIY 

       370 
EGTNEIQRLI ISKYLLGGT

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A sigma E dependent operon subject to catabolite repression during sporulation in Bacillus subtilis." Bryan E.M., Beall B.W., Moran C.P. Jr. J. Bacteriol. 178:4778-4786(1996) [PubMed: 8759838] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], DEVELOPMENTAL STAGE, INDUCTION. Strain: 168 / MB24.
[2]	"Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes." Mizuno M., Masuda S., Takemaru K., Hosono S., Sato T., Takeuchi M., Kobayashi Y. Microbiology 142:3103-3111(1996) [PubMed: 8969508] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168 / JH642.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[4]	"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later." Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A. Microbiology 155:1758-1775(2009) [PubMed: 19383706] [Abstract] Cited for: SEQUENCE REVISION TO 329.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U29084 Genomic DNA. Translation: AAB09615.1. D84432 Genomic DNA. Translation: BAA12589.1. AL009126 Genomic DNA. Translation: CAB14346.2.
PIR	D69658.
RefSeq	NP_390295.2. NC_000964.3.
3D structure databases
ProteinModelPortal	P45857.
SMR	P45857. Positions 1-377.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000001284; EBBACP00000001284; EBBACG00000001282.
GeneID	938664.
GenomeReviews	Gene locus BSU24150 in contig AL009126_GR.
KEGG	bsu:BSU24150.
NMPDR	fig\|224308.1.peg.2419.
PATRIC	18976658. VBIBacSub10457_2519.
Organism-specific databases
GenoList	BSU24150. [Micado]
Phylogenomic databases
GeneTree	EBGT00070000031843.
HOGENOM	HBG699365.
PhylomeDB	P45857.
ProtClustDB	CLSK887543.
Enzyme and pathway databases
BioCyc	BSUB:BSU24150-MONOMER.
Family and domain databases
InterPro	IPR006089. Acyl-CoA_DH_CS. IPR006092. Acyl-CoA_DH_N. IPR006090. Acyl-CoA_Oxase/DH_1. IPR006091. Acyl-CoA_Oxase/DH_cen-dom. IPR009075. AcylCo_DH/oxidase_C. IPR013786. AcylCoA_DH/ox_N. IPR009100. AcylCoA_DH/oxidase. [Graphical view]
Gene3D	G3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit. G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit. G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 1 hit.
KO	K00257.
Pfam	PF00441. Acyl-CoA_dh_1. 1 hit. PF02770. Acyl-CoA_dh_M. 1 hit. PF02771. Acyl-CoA_dh_N. 1 hit. [Graphical view]
SUPFAM	SSF56645. AcylCoA_dehyd_NM. 1 hit. SSF47203. AcylCoADH_C_like. 1 hit.
PROSITE	PS00072. ACYL_COA_DH_1. 1 hit. PS00073. ACYL_COA_DH_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACDB_BACSU

Accession

Primary (citable) accession number: P45857

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	July 7, 2009
Last modified:	January 25, 2012
This is version 88 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents