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Protein

Putative uncharacterized protein HUR1

Gene

HUR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

  • DNA replication Source: SGD
  • macroautophagy Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30656-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative uncharacterized protein HUR1
Gene namesi
Name:HUR1
Ordered Locus Names:YGL168W
ORF Names:G1663
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL168W.
SGDiS000003136. HUR1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 34HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

No increased sensitivity to hydroxyurea.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027281 – 110Putative uncharacterized protein HUR1Add BLAST110

Proteomic databases

PRIDEiP45820.

Interactioni

Protein-protein interaction databases

BioGridi33086. 533 interactors.
DIPiDIP-4765N.
MINTiMINT-556496.
STRINGi4932.YGL168W.

Structurei

3D structure databases

ProteinModelPortaliP45820.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiEOG092C5OWT.

Sequencei

Sequence statusi: Complete.

P45820-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFILVSVVNI CTYIHLHMFP LISTFTSIGL GVLMKDKGKE GKTIKAQNVT
60 70 80 90 100
YQTFEKYVES SSFFFLVHNF LNSSTMKTLL LMSNNNSISE IPSFSVLKIL
110
WKNGIYIAHI
Length:110
Mass (Da):12,515
Last modified:November 1, 1995 - v1
Checksum:i304BF9E60B4F09C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X85757 Genomic DNA. Translation: CAA59761.1.
Z72690 Genomic DNA. Translation: CAA96879.1.
BK006941 Genomic DNA. Translation: DAA07945.1.
PIRiS59652.
RefSeqiNP_011347.1. NM_001181033.1.

Genome annotation databases

EnsemblFungiiYGL168W; YGL168W; YGL168W.
GeneIDi852708.
KEGGisce:YGL168W.

Similar proteinsi

Entry informationi

Entry nameiHUR1_YEAST
AccessioniPrimary (citable) accession number: P45820
Secondary accession number(s): D6VTY4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Deletion HUR1 has been reported to cause increased sensitivity to hydroxyurea (PubMed:12615994). However, HUR1 partially overlaps with PMR1 and a later analysis revealed that deletion of PMR1 but not HUR1 affected resistance to hydroxyurea (PubMed:18069899).2 Publications

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names