P45813 (RS13_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S13

Gene names

Name:	rpsM
Ordered Locus Names:	Mb3489c

Organism

Mycobacterium bovis [Complete proteome] [HAMAP]

Taxonomic identifier

1765 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	124 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites By similarity. HAMAP MF_01315_B
Subunit structure	Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein S13P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 124	124	30S ribosomal protein S13 HAMAP MF_01315_B		PRO_0000132106
Experimental info
	Sequence conflict	2	1	A → D in AAB17598. Ref.1
	Sequence conflict	12	1	D → H in AAB17598. Ref.1
	Sequence conflict	115 – 124	10	RTIAGKKKAR → AHHRRQEEG in AAB17598. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P45813 [UniParc]. Last modified November 28, 2003. Version 2. Checksum: 93B44CB17A4503B1	FASTA	124	14,351
	10 20 30 40 50 60 MARLVGVDLP RDKRMEVALT YIFGIGRTRS NEILAATGID RDLRTRDLTE EQLIHLRDYI 70 80 90 100 110 120 EANLKVEGDL RREVQADIRR KIEIGCYQGL RHRRGMPVRG QRTKTNARTR KGPKRTIAGK KKAR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Overproduction of mycobacterial ribosomal protein S13 induces catalase/peroxidase activity and hypersensitivity to isoniazid in Mycobacterium smegmatis." Dubnau E., Soares S., Huang T.J., Jacobs W.R. Jr. Gene 170:17-22(1996) [PubMed: 8621083] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BCG.
[2]	"The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. , Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G. Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U15140 Genomic DNA. Translation: AAB17598.1. BX248346 Genomic DNA. Translation: CAD95676.1.
RefSeq	NP_857129.1. NC_002945.3.
3D structure databases
ProteinModelPortal	P45813.
SMR	P45813. Positions 2-123.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000015732; EBMYCP00000015567; EBMYCG00000015728.
GeneID	1091096.
GenomeReviews	Gene locus Mb3489c in contig BX248333_GR.
KEGG	mbo:Mb3489c.
PATRIC	18009396. VBIMycBov88188_3826.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015674.
HOGENOM	HBG737405.
OMA	YRGRRHR.
ProtClustDB	PRK05179.
Enzyme and pathway databases
BioCyc	MBOV233413:MB3489C-MONOMER.
Family and domain databases
HAMAP	MF_01315_B. Ribosomal_S13_B. [Tree]
InterPro	IPR001892. Ribosomal_S13. IPR010979. Ribosomal_S13-like_H2TH. IPR019980. Ribosomal_S13_bac-type. IPR018269. Ribosomal_S13_CS. [Graphical view]
KO	K02952.
PANTHER	PTHR10871. PTHR10871. 1 hit.
Pfam	PF00416. Ribosomal_S13. 1 hit. [Graphical view]
PIRSF	PIRSF002134. Ribosomal_S13. 1 hit.
SUPFAM	SSF46946. Ribosomal_H2TH. 1 hit.
TIGRFAMs	TIGR03631. Bact_S13. 1 hit.
PROSITE	PS00646. RIBOSOMAL_S13_1. 1 hit. PS50159. RIBOSOMAL_S13_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS13_MYCBO

Accession

Primary (citable) accession number: P45813

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 28, 2003
Last modified:	January 25, 2012
This is version 70 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program