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P45773

- GSPG_VIBCH

UniProt

P45773 - GSPG_VIBCH

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Protein

Type II secretion system protein G

Gene
epsG, VC_2730
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Required for secretion of cholera toxin through the outer membrane.

GO - Molecular functioni

  1. protein transporter activity Source: InterPro

GO - Biological processi

  1. protein secretion Source: TIGR
  2. protein secretion by the type II secretion system Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciVCHO:VC2730-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Type II secretion system protein G
Short name:
T2SS protein G
Alternative name(s):
Cholera toxin secretion protein EpsG
General secretion pathway protein G
Gene namesi
Name:epsG
Ordered Locus Names:VC_2730
OrganismiVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomic identifieri243277 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000000584: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. type II protein secretion system complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Propeptidei1 – 99 By similarityPRO_0000024210
Chaini10 – 146137Type II secretion system protein GPRO_0000024211Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei10 – 101N-methylphenylalanine By similarity

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi243277.VC2730.

Structurei

Secondary structure

1
146
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi36 – 6328
Turni69 – 713
Helixi73 – 764
Beta strandi93 – 964
Beta strandi107 – 1115
Beta strandi113 – 1219
Turni123 – 1264
Beta strandi127 – 1293
Helixi132 – 1343
Helixi139 – 1457

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FU1X-ray1.90A/B35-146[»]
ProteinModelPortaliP45773.
SMRiP45773. Positions 35-142.

Miscellaneous databases

EvolutionaryTraceiP45773.

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP G family.

Phylogenomic databases

eggNOGiCOG2165.
KOiK02456.
OMAiDIGNWNM.
OrthoDBiEOG657JHX.

Family and domain databases

InterProiIPR000983. Bac_GSPG_pilin.
IPR012902. N_methyl_site.
IPR013545. T2SS_protein-G.
IPR010054. Type2_sec_GspG.
[Graphical view]
PfamiPF13544. N_methyl_2. 1 hit.
PF08334. T2SG. 1 hit.
[Graphical view]
PRINTSiPR00813. BCTERIALGSPG.
TIGRFAMsiTIGR02532. IV_pilin_GFxxxE. 1 hit.
TIGR01710. typeII_sec_gspG. 1 hit.
PROSITEiPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45773-1 [UniParc]FASTAAdd to Basket

« Hide

MKKMRKQTGF TLLEVMVVVV ILGILASFVV PNLLGNKEKA DQQKAVTDIV    50
ALENALDMYK LDNSVYPTTD QGLEALVTKP TNPEPRNYRE GGYIKRLPKD 100
PWGNDYQYLS PGDKGTIDVF TLGADGQEGG EGTGADIGNW NIQDFQ 146
Length:146
Mass (Da):16,080
Last modified:November 1, 1995 - v1
Checksum:i2B211AA994761E2A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L33796 Genomic DNA. Translation: AAA58788.1.
AE003852 Genomic DNA. Translation: AAF95870.1.
PIRiD82041.
RefSeqiNP_232357.1. NC_002505.1.
WP_000738789.1. NC_002505.1.

Genome annotation databases

EnsemblBacteriaiAAF95870; AAF95870; VC_2730.
GeneIDi2614893.
KEGGivch:VC2730.
PATRICi20084478. VBIVibCho83274_2605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L33796 Genomic DNA. Translation: AAA58788.1 .
AE003852 Genomic DNA. Translation: AAF95870.1 .
PIRi D82041.
RefSeqi NP_232357.1. NC_002505.1.
WP_000738789.1. NC_002505.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3FU1 X-ray 1.90 A/B 35-146 [» ]
ProteinModelPortali P45773.
SMRi P45773. Positions 35-142.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243277.VC2730.

Protocols and materials databases

DNASUi 2614893.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF95870 ; AAF95870 ; VC_2730 .
GeneIDi 2614893.
KEGGi vch:VC2730.
PATRICi 20084478. VBIVibCho83274_2605.

Phylogenomic databases

eggNOGi COG2165.
KOi K02456.
OMAi DIGNWNM.
OrthoDBi EOG657JHX.

Enzyme and pathway databases

BioCyci VCHO:VC2730-MONOMER.

Miscellaneous databases

EvolutionaryTracei P45773.

Family and domain databases

InterProi IPR000983. Bac_GSPG_pilin.
IPR012902. N_methyl_site.
IPR013545. T2SS_protein-G.
IPR010054. Type2_sec_GspG.
[Graphical view ]
Pfami PF13544. N_methyl_2. 1 hit.
PF08334. T2SG. 1 hit.
[Graphical view ]
PRINTSi PR00813. BCTERIALGSPG.
TIGRFAMsi TIGR02532. IV_pilin_GFxxxE. 1 hit.
TIGR01710. typeII_sec_gspG. 1 hit.
PROSITEi PS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Organization of the general secretion pathway genes in Vibrio cholerae."
    Overbye L.J.
    Thesis (1994), Michigan State University, United States
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: El Tor TRH7000.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39315 / El Tor Inaba N16961.

Entry informationi

Entry nameiGSPG_VIBCH
AccessioniPrimary (citable) accession number: P45773
Secondary accession number(s): Q9JPZ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 3, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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