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P45773 (GSPG_VIBCH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type II secretion system protein G

Short name=T2SS protein G
Alternative name(s):
Cholera toxin secretion protein EpsG
General secretion pathway protein G
Gene names
Name:epsG
Ordered Locus Names:VC_2730
OrganismVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [Reference proteome] [HAMAP]
Taxonomic identifier243277 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length146 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Required for secretion of cholera toxin through the outer membrane.

Sequence similarities

Belongs to the GSP G family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Propeptide1 – 99 By similarity
PRO_0000024210
Chain10 – 146137Type II secretion system protein G
PRO_0000024211

Amino acid modifications

Modified residue101N-methylphenylalanine By similarity

Secondary structure

.................... 146
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P45773 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 2B211AA994761E2A

FASTA14616,080
        10         20         30         40         50         60 
MKKMRKQTGF TLLEVMVVVV ILGILASFVV PNLLGNKEKA DQQKAVTDIV ALENALDMYK 

        70         80         90        100        110        120 
LDNSVYPTTD QGLEALVTKP TNPEPRNYRE GGYIKRLPKD PWGNDYQYLS PGDKGTIDVF 

       130        140 
TLGADGQEGG EGTGADIGNW NIQDFQ 

« Hide

References

« Hide 'large scale' references
[1]"Organization of the general secretion pathway genes in Vibrio cholerae."
Overbye L.J.
Thesis (1994), Michigan State University, United States
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: El Tor TRH7000.
[2]"DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae."
Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D., Vamathevan J.J., Bass S. expand/collapse author list , Qin H., Dragoi I., Sellers P., McDonald L.A., Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L., Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.
Nature 406:477-483(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39315 / El Tor Inaba N16961.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L33796 Genomic DNA. Translation: AAA58788.1.
AE003852 Genomic DNA. Translation: AAF95870.1.
PIRD82041.
RefSeqNP_232357.1. NC_002505.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3FU1X-ray1.90A/B35-146[»]
ProteinModelPortalP45773.
SMRP45773. Positions 35-142.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243277.VC2730.

Protocols and materials databases

DNASU2614893.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF95870; AAF95870; VC_2730.
GeneID2614893.
KEGGvch:VC2730.
PATRIC20084478. VBIVibCho83274_2605.

Phylogenomic databases

eggNOGCOG2165.
KOK02456.
OMADIGNWNM.
OrthoDBEOG657JHX.
ProtClustDBCLSK874901.

Enzyme and pathway databases

BioCycVCHO:VC2730-MONOMER.

Family and domain databases

InterProIPR000983. Bac_GSPG_pilin.
IPR012902. N_methyl_site.
IPR013545. T2SS_protein-G.
IPR010054. Type2_sec_GspG.
[Graphical view]
PfamPF13544. N_methyl_2. 1 hit.
PF08334. T2SG. 1 hit.
[Graphical view]
PRINTSPR00813. BCTERIALGSPG.
TIGRFAMsTIGR02532. IV_pilin_GFxxxE. 1 hit.
TIGR01710. typeII_sec_gspG. 1 hit.
PROSITEPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP45773.

Entry information

Entry nameGSPG_VIBCH
AccessionPrimary (citable) accession number: P45773
Secondary accession number(s): Q9JPZ6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: December 11, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references