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Protein

Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ

Gene

yhdZ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably part of a binding-protein-dependent transport system YdhWXYZ for an amino acid. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi45 – 52ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:YHDZ-MONOMER.
ECOL316407:JW3239-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.26. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZ
Gene namesi
Name:yhdZ
Ordered Locus Names:b3271, JW3239
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12837. yhdZ.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931691 – 252Uncharacterized amino-acid ABC transporter ATP-binding protein YhdZAdd BLAST252

Proteomic databases

EPDiP45769.
PaxDbiP45769.
PRIDEiP45769.

Interactioni

Protein-protein interaction databases

BioGridi4262453. 51 interactors.
IntActiP45769. 4 interactors.
STRINGi511145.b3271.

Structurei

3D structure databases

ProteinModelPortaliP45769.
SMRiP45769.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 247ABC transporterPROSITE-ProRule annotationAdd BLAST235

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105CDA. Bacteria.
COG1126. LUCA.
InParanoidiP45769.
KOiK09972.
OMAiEPMILLQ.
PhylomeDBiP45769.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR030679. ABC_ATPase_HisP-typ.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
PIRSFiPIRSF039085. ABC_ATPase_HisP. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P45769-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQILLQPAN AMITLENVNK WYGQFHVLKN INLTVQPGER IVLCGPSGSG
60 70 80 90 100
KSTTIRCINH LEEHQQGRIV VDGIELNEDI RNIERVRQEV GMVFQHFNLF
110 120 130 140 150
PHLTVLQNCT LAPIWVRKMP KKEAEDLAVH YLERVRIAEH AHKFPGQISG
160 170 180 190 200
GQQQRVAIAR SLCMKPKIML FDEPTSALDP EMVKEVLDTM IGLAQSGMTM
210 220 230 240 250
LCVTHEMGFA RTVADRVIFM DRGEIVEQAA PDEFFAHPKS ERTRAFLSQV

IH
Length:252
Mass (Da):28,574
Last modified:November 1, 1995 - v1
Checksum:iCDB128CC6C32CDAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58075.1.
U00096 Genomic DNA. Translation: AAC76303.1.
AP009048 Genomic DNA. Translation: BAE77312.1.
PIRiA65120.
RefSeqiNP_417737.1. NC_000913.3.
WP_000078349.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76303; AAC76303; b3271.
BAE77312; BAE77312; BAE77312.
GeneIDi947763.
KEGGiecj:JW3239.
eco:b3271.
PATRICi32121974. VBIEscCol129921_3371.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58075.1.
U00096 Genomic DNA. Translation: AAC76303.1.
AP009048 Genomic DNA. Translation: BAE77312.1.
PIRiA65120.
RefSeqiNP_417737.1. NC_000913.3.
WP_000078349.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45769.
SMRiP45769.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262453. 51 interactors.
IntActiP45769. 4 interactors.
STRINGi511145.b3271.

Protein family/group databases

TCDBi3.A.1.3.26. the atp-binding cassette (abc) superfamily.

Proteomic databases

EPDiP45769.
PaxDbiP45769.
PRIDEiP45769.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76303; AAC76303; b3271.
BAE77312; BAE77312; BAE77312.
GeneIDi947763.
KEGGiecj:JW3239.
eco:b3271.
PATRICi32121974. VBIEscCol129921_3371.

Organism-specific databases

EchoBASEiEB2686.
EcoGeneiEG12837. yhdZ.

Phylogenomic databases

eggNOGiENOG4105CDA. Bacteria.
COG1126. LUCA.
InParanoidiP45769.
KOiK09972.
OMAiEPMILLQ.
PhylomeDBiP45769.

Enzyme and pathway databases

BioCyciEcoCyc:YHDZ-MONOMER.
ECOL316407:JW3239-MONOMER.

Miscellaneous databases

PROiP45769.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR030679. ABC_ATPase_HisP-typ.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
PIRSFiPIRSF039085. ABC_ATPase_HisP. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHDZ_ECOLI
AccessioniPrimary (citable) accession number: P45769
Secondary accession number(s): Q2M8U4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.