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Protein

Inner membrane amino-acid ABC transporter permease protein YhdY

Gene

yhdY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHDY-MONOMER

Protein family/group databases

TCDBi3.A.1.3.26 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane amino-acid ABC transporter permease protein YhdY
Gene namesi
Name:yhdY
Ordered Locus Names:b3270, JW5545
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12836 yhdY

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 36CytoplasmicSequence analysisAdd BLAST36
Transmembranei37 – 57HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini58 – 99PeriplasmicSequence analysisAdd BLAST42
Transmembranei100 – 120HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini121 – 125CytoplasmicSequence analysis5
Transmembranei126 – 146HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini147 – 162PeriplasmicSequence analysisAdd BLAST16
Transmembranei163 – 183HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini184 – 192CytoplasmicSequence analysis9
Transmembranei193 – 213HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini214 – 233PeriplasmicSequence analysisAdd BLAST20
Transmembranei234 – 254HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini255 – 291CytoplasmicSequence analysisAdd BLAST37
Transmembranei292 – 312HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini313 – 326PeriplasmicSequence analysisAdd BLAST14
Transmembranei327 – 347HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini348 – 367CytoplasmicSequence analysisAdd BLAST20

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: InterPro
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602541 – 367Inner membrane amino-acid ABC transporter permease protein YhdYAdd BLAST367

Proteomic databases

PaxDbiP45768
PRIDEiP45768

Interactioni

Protein-protein interaction databases

BioGridi4261009, 8 interactors
DIPiDIP-12306N
IntActiP45768, 3 interactors
STRINGi316385.ECDH10B_3445

Structurei

3D structure databases

ProteinModelPortaliP45768
SMRiP45768
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 353ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST195

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DRP Bacteria
COG0765 LUCA
HOGENOMiHOG000125341
InParanoidiP45768
KOiK09971
OMAiLVFWVFC
PhylomeDBiP45768

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR010065 AA_ABC_transptr_permease_3TM
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
TIGRFAMsiTIGR01726 HEQRo_perm_3TM, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P45768-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVLLSHPP RPASHNSSRA MVWVRKNLFS SWSNSLLTIG CIWLMWELIP
60 70 80 90 100
PLLNWAFLQA NWVGSTRADC TKAGACWVFI HERFGQFMYG LYPHDQRWRI
110 120 130 140 150
NLALLIGLVS IAPMFWKILP HRGRYIAAWA VIYPLIVWWL MYGGFFALER
160 170 180 190 200
VETRQWGGLT LTLIIASVGI AGALPWGILL ALGRRSHMPI VRILSVIFIE
210 220 230 240 250
FWRGVPLITV LFMSSVMLPL FMAEGTSIDK LIRALVGVIL FQSAYVAEVV
260 270 280 290 300
RGGLQALPKG QYEAAESLAL GYWKTQGLVI LPQALKLVIP GLVNTIIALF
310 320 330 340 350
KDTSLVIIIG LFDLFSSVQQ ATVDPAWLGM STEGYVFAAL IYWIFCFSMS
360
RYSQYLEKRF NTGRTPH
Length:367
Mass (Da):41,484
Last modified:December 15, 1998 - v2
Checksum:iEC95E04BBC7418D1
GO

Sequence cautioni

The sequence AAA58074 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58074.1 Different initiation.
U00096 Genomic DNA Translation: AAC76302.2
AP009048 Genomic DNA Translation: BAE77311.1
PIRiH65119
RefSeqiNP_417736.2, NC_000913.3
WP_001300681.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76302; AAC76302; b3270
BAE77311; BAE77311; BAE77311
GeneIDi947764
KEGGiecj:JW5545
eco:b3270
PATRICifig|511145.12.peg.3370

Similar proteinsi

Entry informationi

Entry nameiYHDY_ECOLI
AccessioniPrimary (citable) accession number: P45768
Secondary accession number(s): Q2M8U5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 15, 1998
Last modified: March 28, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health