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Protein

Putative amino-acid ABC transporter permease protein YhdX

Gene

yhdX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHDX-MONOMER

Protein family/group databases

TCDBi3.A.1.3.26 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Putative amino-acid ABC transporter permease protein YhdX
Gene namesi
Name:yhdX
Ordered Locus Names:b3269, JW5544
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12835 yhdX

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 41HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei92 – 112HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei128 – 148HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei180 – 200HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei219 – 239HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei256 – 276HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei333 – 353HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei363 – 383HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: InterPro
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602531 – 393Putative amino-acid ABC transporter permease protein YhdXAdd BLAST393

Proteomic databases

PaxDbiP45767
PRIDEiP45767

Interactioni

Protein-protein interaction databases

BioGridi4260867, 5 interactors
STRINGi316385.ECDH10B_3444

Structurei

3D structure databases

ProteinModelPortaliP45767
SMRiP45767
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 381ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST294

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EZ7 Bacteria
COG4597 LUCA
HOGENOMiHOG000267553
InParanoidiP45767
KOiK09970
OMAiILFWYFA
PhylomeDBiP45767

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 2 hits
InterProiView protein in InterPro
IPR010065 AA_ABC_transptr_permease_3TM
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 2 hits
TIGRFAMsiTIGR01726 HEQRo_perm_3TM, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P45767-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHRRSTVKG SLSFANPTVR AWLFQILAVV AVVGIVGWLF HNTVTNLNNR
60 70 80 90 100
GITSGFAFLD RGAGFGIVQH LIDYQQGDTY GRVFIVGLLN TLLVSALCIV
110 120 130 140 150
FASVLGFFIG LARLSDNWLL RKLSTIYIEI FRNIPPLLQI FFWYFAVLRN
160 170 180 190 200
LPGPRQAVSA FDLAFLSNRG LYIPSPQLGD GFIAFILAVV MAIVLSVGLF
210 220 230 240 250
RFNKTYQIKT GQLRRTWPIA AVLIIGLPLL AQWLFGAALH WDVPALRGFN
260 270 280 290 300
FRGGMVLIPE LAALTLALSV YTSAFIAEII RAGIQAVPYG QHEAARSLGL
310 320 330 340 350
PNPVTLRQVI IPQALRVIIP PLTSQYLNIV KNSSLAAAIG YPDMVSLFAG
360 370 380 390
TVLNQTGQAI ETIAMTMSVY LIISLTISLL MNIYNRRIAI VER
Length:393
Mass (Da):43,261
Last modified:October 11, 2004 - v3
Checksum:iEE95D98184216D22
GO

Sequence cautioni

The sequence AAA58073 differs from that shown. Reason: Frameshift at position 358.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58073.1 Frameshift.
U00096 Genomic DNA Translation: AAT48174.1
AP009048 Genomic DNA Translation: BAE77310.1
RefSeqiWP_000019655.1, NZ_LN832404.1
YP_026209.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAT48174; AAT48174; b3269
BAE77310; BAE77310; BAE77310
GeneIDi947765
KEGGiecj:JW5544
eco:b3269
PATRICifig|1411691.4.peg.3458

Similar proteinsi

Entry informationi

Entry nameiYHDX_ECOLI
AccessioniPrimary (citable) accession number: P45767
Secondary accession number(s): Q2M8U6, Q6BF40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 121 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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