Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative amino-acid ABC transporter permease protein YhdX

Gene

yhdX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHDX-MONOMER.
ECOL316407:JW5544-MONOMER.
RETL1328306-WGS:GSTH-1952-MONOMER.
RETL1328306-WGS:GSTH-4591-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.26. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative amino-acid ABC transporter permease protein YhdX
Gene namesi
Name:yhdX
Ordered Locus Names:b3269, JW5544
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12835. yhdX.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei92 – 11221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei128 – 14821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei180 – 20021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei219 – 23921HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei256 – 27621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei333 – 35321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei363 – 38321HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Putative amino-acid ABC transporter permease protein YhdXPRO_0000060253Add
BLAST

Proteomic databases

PaxDbiP45767.

Interactioni

Protein-protein interaction databases

BioGridi4260867. 5 interactions.
STRINGi511145.b3269.

Structurei

3D structure databases

ProteinModelPortaliP45767.
SMRiP45767. Positions 258-388.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini88 – 381294ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EZ7. Bacteria.
COG4597. LUCA.
HOGENOMiHOG000267553.
InParanoidiP45767.
KOiK09970.
OMAiSTIYIET.
PhylomeDBiP45767.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 2 hits.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P45767-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHRRSTVKG SLSFANPTVR AWLFQILAVV AVVGIVGWLF HNTVTNLNNR
60 70 80 90 100
GITSGFAFLD RGAGFGIVQH LIDYQQGDTY GRVFIVGLLN TLLVSALCIV
110 120 130 140 150
FASVLGFFIG LARLSDNWLL RKLSTIYIEI FRNIPPLLQI FFWYFAVLRN
160 170 180 190 200
LPGPRQAVSA FDLAFLSNRG LYIPSPQLGD GFIAFILAVV MAIVLSVGLF
210 220 230 240 250
RFNKTYQIKT GQLRRTWPIA AVLIIGLPLL AQWLFGAALH WDVPALRGFN
260 270 280 290 300
FRGGMVLIPE LAALTLALSV YTSAFIAEII RAGIQAVPYG QHEAARSLGL
310 320 330 340 350
PNPVTLRQVI IPQALRVIIP PLTSQYLNIV KNSSLAAAIG YPDMVSLFAG
360 370 380 390
TVLNQTGQAI ETIAMTMSVY LIISLTISLL MNIYNRRIAI VER
Length:393
Mass (Da):43,261
Last modified:October 11, 2004 - v3
Checksum:iEE95D98184216D22
GO

Sequence cautioni

The sequence AAA58073 differs from that shown. Reason: Frameshift at position 358. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58073.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48174.1.
AP009048 Genomic DNA. Translation: BAE77310.1.
RefSeqiWP_000019655.1. NZ_LN832404.1.
YP_026209.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48174; AAT48174; b3269.
BAE77310; BAE77310; BAE77310.
GeneIDi947765.
KEGGiecj:JW5544.
eco:b3269.
PATRICi32121970. VBIEscCol129921_3369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58073.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48174.1.
AP009048 Genomic DNA. Translation: BAE77310.1.
RefSeqiWP_000019655.1. NZ_LN832404.1.
YP_026209.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP45767.
SMRiP45767. Positions 258-388.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260867. 5 interactions.
STRINGi511145.b3269.

Protein family/group databases

TCDBi3.A.1.3.26. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP45767.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48174; AAT48174; b3269.
BAE77310; BAE77310; BAE77310.
GeneIDi947765.
KEGGiecj:JW5544.
eco:b3269.
PATRICi32121970. VBIEscCol129921_3369.

Organism-specific databases

EchoBASEiEB2684.
EcoGeneiEG12835. yhdX.

Phylogenomic databases

eggNOGiENOG4105EZ7. Bacteria.
COG4597. LUCA.
HOGENOMiHOG000267553.
InParanoidiP45767.
KOiK09970.
OMAiSTIYIET.
PhylomeDBiP45767.

Enzyme and pathway databases

BioCyciEcoCyc:YHDX-MONOMER.
ECOL316407:JW5544-MONOMER.
RETL1328306-WGS:GSTH-1952-MONOMER.
RETL1328306-WGS:GSTH-4591-MONOMER.

Miscellaneous databases

PROiP45767.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 2 hits.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYHDX_ECOLI
AccessioniPrimary (citable) accession number: P45767
Secondary accession number(s): Q2M8U6, Q6BF40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 112 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.