P45766 (YHDW_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative amino-acid ABC transporter-binding protein YhdW

Gene names

Name:	yhdW
Ordered Locus Names:	b3268, JW3236

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Uncertain

General annotation (Comments)

Function	Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid.
Subcellular location	Periplasm Probable.
Sequence similarities	Belongs to the bacterial solute-binding protein 3 family.
Caution	Could be the product of a pseudogene.
Sequence caution	The sequence AAA58072.1 differs from that shown. Reason: Frameshift at position 23. The sequence U00096 differs from that shown. Reason: Frameshift at position 23.

Ontologies

Keywords
Biological process	Amino-acid transport Transport
Cellular component	Periplasm
Domain	Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	amino acid transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 341	322	Putative amino-acid ABC transporter-binding protein YhdW		PRO_0000031774

Sequences

	Sequence		Length	Mass (Da)
	P45766 [UniParc]. Last modified May 4, 2001. Version 2. Checksum: 404FE51DB30FBB40	FASTA	341	37,021
	10 20 30 40 50 60 MKKMMIATLA AASVLLAVAN QAXAGATLDA VQKKGFVQCG ISDGLPGFSY ADADGKFSGI 70 80 90 100 110 120 DVDICRGVAA AVFGDDTKVK YTPLTAKERF TALQSGEVDL LSRNTTWTSS RDAGMGMAFT 130 140 150 160 170 180 GVTYYDGIGF LTHDKAGLKS AKELDGATVC IQAGTDTELN VADYFKANNM KYTPVTFDRS 190 200 210 220 230 240 DESAKALESG RCDTLASDQS QLYALRIKLS NPAEWIVLPE VISKEPLGPV VRRGDDEWFS 250 260 270 280 290 300 IVRWTLFAML NAEEMGINSQ NVDEKAANPA TPDMAHLLGK EGDYGKDLKL DNKWAYNIIK 310 320 330 340 QVGNYSEIFE RNVGSESPLK IKRGQNNLWN NGGIQYAPPV R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography." Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B. Electrophoresis 20:2181-2195(1999) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY. Strain: B / BL21.
[4]	Rudd K.E. Unpublished observations (JAN-2000) Cited for: CONCEPTUAL TRANSLATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U18997 Genomic DNA. Translation: AAA58072.1. Frameshift. U00096 Genomic DNA. No translation available. AP009048 Genomic DNA. Translation: BAE77309.1. Frameshift.
PIR	F65119.
RefSeq	YP_491450.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P45766.
SMR	P45766. Positions 23-238.
ModBase	Search...
Protein-protein interaction databases
STRING	316407.yhdW.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAE77309; BAE77309; BAE77309.
GeneID	12934173.
KEGG	ecj:Y75_p3186.
PATRIC	48665997. VBIEscCol107702_3301.
Organism-specific databases
EchoBASE	EB2683.
EcoGene	EG12834. yhdW.
Phylogenomic databases
eggNOG	COG0834.
HOGENOM	HOG000003595.
KO	K09969.
OMA	YFKANKM.
Enzyme and pathway databases
BioCyc	EcoCyc:YHDW-MONOMER. ECOL316407:JW3236-MONOMER.
Gene expression databases
Genevestigator	P45766.
Family and domain databases
InterPro	IPR001638. SBP_bac_3. IPR018313. SBP_bac_3_CS. [Graphical view]
Pfam	PF00497. SBP_bac_3. 1 hit. [Graphical view]
SMART	SM00062. PBPb. 1 hit. [Graphical view]
PROSITE	PS01039. SBP_BACTERIAL_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YHDW_ECOLI

Accession

Primary (citable) accession number: P45766
Secondary accession number(s): Q2M8U7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	May 4, 2001
Last modified:	May 1, 2013
This is version 94 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program