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Protein

Putative DNA utilization protein HofM

Gene

hofM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Required for the use of extracellular DNA as a nutrient.1 Publication

GO - Biological processi

  • carbon utilization Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7739-MONOMER.
ECOL316407:JW5693-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative DNA utilization protein HofM
Gene namesi
Name:hofM
Synonyms:yrfD
Ordered Locus Names:b3395, JW5693
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12925. hofM.

Pathology & Biotechi

Disruption phenotypei

Mutants are unable to use DNA as a sole carbon and energy source.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695411 – 259Putative DNA utilization protein HofMAdd BLAST259

Proteomic databases

PaxDbiP45753.
PRIDEiP45753.

Interactioni

Protein-protein interaction databases

BioGridi4260909. 9 interactors.
DIPiDIP-12921N.
IntActiP45753. 1 interactor.
MINTiMINT-1288735.
STRINGi511145.b3395.

Structurei

3D structure databases

ProteinModelPortaliP45753.
SMRiP45753.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108U1Q. Bacteria.
ENOG4111I00. LUCA.
HOGENOMiHOG000125553.
KOiK12288.
OMAiTMAFKIW.

Sequencei

Sequence statusi: Complete.

P45753-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFKIWQIGL HLQQQEAVAV AIVRGAKECF LQRWWRLPLE NDIIKDGRIV
60 70 80 90 100
DAQQLAKTLL PWSRELPQRH HIMLAFPASR TLQRSFPRPS MSLGEREQTA
110 120 130 140 150
WLSGTMAREL DMDPDSLRFD YSEDSLSPAY NVTAAQSKEL ATLLTLAERL
160 170 180 190 200
RVHVSAITPD ASALQRFLPF LPSHQQCLAW RDNEQWLWAT RYSWGRKLAV
210 220 230 240 250
GMTSAKELAA ALSVDPESVA ICGEGGFDPW EAVSVRQPPL PPPGGDFAIA

LGLALGKAY
Length:259
Mass (Da):29,000
Last modified:December 1, 2000 - v2
Checksum:iB3E8B4A0E4AB166D
GO

Sequence cautioni

The sequence AAA58192 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58192.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76420.2.
AP009048 Genomic DNA. Translation: BAE77896.1.
PIRiF65134.
RefSeqiNP_417854.4. NC_000913.3.
WP_001295166.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76420; AAC76420; b3395.
BAE77896; BAE77896; BAE77896.
GeneIDi947908.
KEGGiecj:JW5693.
eco:b3395.
PATRICi32122222. VBIEscCol129921_3488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58192.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76420.2.
AP009048 Genomic DNA. Translation: BAE77896.1.
PIRiF65134.
RefSeqiNP_417854.4. NC_000913.3.
WP_001295166.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45753.
SMRiP45753.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260909. 9 interactors.
DIPiDIP-12921N.
IntActiP45753. 1 interactor.
MINTiMINT-1288735.
STRINGi511145.b3395.

Proteomic databases

PaxDbiP45753.
PRIDEiP45753.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76420; AAC76420; b3395.
BAE77896; BAE77896; BAE77896.
GeneIDi947908.
KEGGiecj:JW5693.
eco:b3395.
PATRICi32122222. VBIEscCol129921_3488.

Organism-specific databases

EchoBASEiEB2761.
EcoGeneiEG12925. hofM.

Phylogenomic databases

eggNOGiENOG4108U1Q. Bacteria.
ENOG4111I00. LUCA.
HOGENOMiHOG000125553.
KOiK12288.
OMAiTMAFKIW.

Enzyme and pathway databases

BioCyciEcoCyc:G7739-MONOMER.
ECOL316407:JW5693-MONOMER.

Miscellaneous databases

PROiP45753.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiHOFM_ECOLI
AccessioniPrimary (citable) accession number: P45753
Secondary accession number(s): Q2M760
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 1, 2000
Last modified: November 2, 2016
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.