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Protein

DNA utilization protein HofO

Gene

hofO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Required for the use of extracellular DNA as a nutrient.1 Publication

GO - Biological processi

  • carbon utilization Source: EcoCyc
  • DNA catabolic process Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7737-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA utilization protein HofO
Gene namesi
Name:hofO
Synonyms:yrfB
Ordered Locus Names:b3393, JW3356
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12923 hofO

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 37HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mutants are unable to use DNA as a sole carbon and energy source and show decreased competitive fitness when cocultured with wild-type cells.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695381 – 146DNA utilization protein HofOAdd BLAST146

Proteomic databases

PaxDbiP45751
PRIDEiP45751

Interactioni

Protein-protein interaction databases

BioGridi42624846 interactors.
DIPiDIP-12919N
IntActiP45751 4 interactors.
STRINGi316385.ECDH10B_3568

Structurei

3D structure databases

ProteinModelPortaliP45751
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105XPX Bacteria
ENOG411265W LUCA
HOGENOMiHOG000125521
KOiK12290
OMAiWLARCGM

Sequencei

Sequence statusi: Complete.

P45751-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMFFDWWFA TSPRLRQLCW AFWLLMLVTL IFLSSTHHEE RDALIRLRAS
60 70 80 90 100
HHQQWAALYR LVDTAPFSEE KTLPFSPLDF QLSGAQLVSW HPSAQGGELA
110 120 130 140
LKTLWEAVPS AFTRLAERNV SVSRFSLSVE GDDLLFTLQL ETPHEG
Length:146
Mass (Da):16,846
Last modified:November 1, 1995 - v1
Checksum:i96548622C7D0374B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA58190.1
U00096 Genomic DNA Translation: AAC76418.1
AP009048 Genomic DNA Translation: BAE77898.1
PIRiD65134
RefSeqiNP_417852.1, NC_000913.3
WP_001055759.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76418; AAC76418; b3393
BAE77898; BAE77898; BAE77898
GeneIDi947899
KEGGiecj:JW3356
eco:b3393
PATRICifig|1411691.4.peg.3337

Similar proteinsi

Entry informationi

Entry nameiHOFO_ECOLI
AccessioniPrimary (citable) accession number: P45751
Secondary accession number(s): Q2M758
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome