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Protein

Putative DNA utilization protein HofO

Gene

hofO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Required for the use of extracellular DNA as a nutrient.1 Publication

GO - Biological processi

  • carbon utilization Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7737-MONOMER.
ECOL316407:JW3356-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative DNA utilization protein HofO
Gene namesi
Name:hofO
Synonyms:yrfB
Ordered Locus Names:b3393, JW3356
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12923. hofO.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 37HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mutants are unable to use DNA as a sole carbon and energy source and show decreased competitive fitness when cocultured with wild-type cells.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695381 – 146Putative DNA utilization protein HofOAdd BLAST146

Proteomic databases

PaxDbiP45751.
PRIDEiP45751.

Interactioni

Protein-protein interaction databases

BioGridi4262484. 6 interactors.
DIPiDIP-12919N.
IntActiP45751. 4 interactors.
MINTiMINT-1287965.
STRINGi511145.b3393.

Structurei

3D structure databases

ProteinModelPortaliP45751.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105XPX. Bacteria.
ENOG411265W. LUCA.
HOGENOMiHOG000125521.
KOiK12290.
OMAiDMLFDWW.

Sequencei

Sequence statusi: Complete.

P45751-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMFFDWWFA TSPRLRQLCW AFWLLMLVTL IFLSSTHHEE RDALIRLRAS
60 70 80 90 100
HHQQWAALYR LVDTAPFSEE KTLPFSPLDF QLSGAQLVSW HPSAQGGELA
110 120 130 140
LKTLWEAVPS AFTRLAERNV SVSRFSLSVE GDDLLFTLQL ETPHEG
Length:146
Mass (Da):16,846
Last modified:November 1, 1995 - v1
Checksum:i96548622C7D0374B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58190.1.
U00096 Genomic DNA. Translation: AAC76418.1.
AP009048 Genomic DNA. Translation: BAE77898.1.
PIRiD65134.
RefSeqiNP_417852.1. NC_000913.3.
WP_001055759.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76418; AAC76418; b3393.
BAE77898; BAE77898; BAE77898.
GeneIDi947899.
KEGGiecj:JW3356.
eco:b3393.
PATRICi32122218. VBIEscCol129921_3486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58190.1.
U00096 Genomic DNA. Translation: AAC76418.1.
AP009048 Genomic DNA. Translation: BAE77898.1.
PIRiD65134.
RefSeqiNP_417852.1. NC_000913.3.
WP_001055759.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45751.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262484. 6 interactors.
DIPiDIP-12919N.
IntActiP45751. 4 interactors.
MINTiMINT-1287965.
STRINGi511145.b3393.

Proteomic databases

PaxDbiP45751.
PRIDEiP45751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76418; AAC76418; b3393.
BAE77898; BAE77898; BAE77898.
GeneIDi947899.
KEGGiecj:JW3356.
eco:b3393.
PATRICi32122218. VBIEscCol129921_3486.

Organism-specific databases

EchoBASEiEB2759.
EcoGeneiEG12923. hofO.

Phylogenomic databases

eggNOGiENOG4105XPX. Bacteria.
ENOG411265W. LUCA.
HOGENOMiHOG000125521.
KOiK12290.
OMAiDMLFDWW.

Enzyme and pathway databases

BioCyciEcoCyc:G7737-MONOMER.
ECOL316407:JW3356-MONOMER.

Miscellaneous databases

PROiP45751.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiHOFO_ECOLI
AccessioniPrimary (citable) accession number: P45751
Secondary accession number(s): Q2M758
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.