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Protein

Putative DNA utilization protein HofP

Gene

hofP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Required for the use of extracellular DNA as a nutrient.1 Publication

GO - Biological processi

  • carbon utilization Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7736-MONOMER.
ECOL316407:JW5694-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative DNA utilization protein HofP
Gene namesi
Name:hofP
Synonyms:yrfA
Ordered Locus Names:b3392, JW5694
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12922. hofP.

Pathology & Biotechi

Disruption phenotypei

Mutants are unable to use DNA as a sole carbon and energy source and show decreased competitive fitness when cocultured with wild-type cells.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001695371 – 134Putative DNA utilization protein HofPAdd BLAST134

Proteomic databases

PaxDbiP45750.
PRIDEiP45750.

Interactioni

Protein-protein interaction databases

BioGridi4261393. 8 interactors.
STRINGi511145.b3392.

Structurei

3D structure databases

ProteinModelPortaliP45750.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105ITY. Bacteria.
ENOG4111S65. LUCA.
HOGENOMiHOG000268031.
KOiK12291.
OMAiQWRYQGI.

Family and domain databases

InterProiIPR019684. DUF2531.
[Graphical view]
PfamiPF10748. DUF2531. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P45750-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVKRWLLAG IALCLLTGMR DPFKPPEDLC RISELSQWRY QGMVGRGERI
60 70 80 90 100
IGVIKDGQKK WRRVQQNDVL ENGWTILQLT PDVLTLGTGT NCEPPQWLWQ
110 120 130
RQGDTNEAMD SRTTVDADTR RTGGKAAKSD ADGG
Length:134
Mass (Da):15,098
Last modified:December 1, 2000 - v3
Checksum:iF6C5010E3127D056
GO

Sequence cautioni

The sequence AAA58189 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58189.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76417.2.
AP009048 Genomic DNA. Translation: BAE77899.1.
PIRiC65134.
RefSeqiNP_417851.4. NC_000913.3.
WP_001264141.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76417; AAC76417; b3392.
BAE77899; BAE77899; BAE77899.
GeneIDi947900.
KEGGiecj:JW5694.
eco:b3392.
PATRICi32122216. VBIEscCol129921_3485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58189.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76417.2.
AP009048 Genomic DNA. Translation: BAE77899.1.
PIRiC65134.
RefSeqiNP_417851.4. NC_000913.3.
WP_001264141.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45750.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261393. 8 interactors.
STRINGi511145.b3392.

Proteomic databases

PaxDbiP45750.
PRIDEiP45750.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76417; AAC76417; b3392.
BAE77899; BAE77899; BAE77899.
GeneIDi947900.
KEGGiecj:JW5694.
eco:b3392.
PATRICi32122216. VBIEscCol129921_3485.

Organism-specific databases

EchoBASEiEB2758.
EcoGeneiEG12922. hofP.

Phylogenomic databases

eggNOGiENOG4105ITY. Bacteria.
ENOG4111S65. LUCA.
HOGENOMiHOG000268031.
KOiK12291.
OMAiQWRYQGI.

Enzyme and pathway databases

BioCyciEcoCyc:G7736-MONOMER.
ECOL316407:JW5694-MONOMER.

Miscellaneous databases

PROiP45750.

Family and domain databases

InterProiIPR019684. DUF2531.
[Graphical view]
PfamiPF10748. DUF2531. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHOFP_ECOLI
AccessioniPrimary (citable) accession number: P45750
Secondary accession number(s): Q2M757
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 1, 2000
Last modified: November 2, 2016
This is version 87 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.