Reviewed, UniProtKB/Swiss-Prot P45739 (CATA_HELAN)

Names and origin

Protein names	Recommended name:     Catalase     EC=1.11.1.6
Organism	Helianthus annuus (Common sunflower)
Taxonomic identifier	4232 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Heliantheae › Helianthus

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group.
Subunit structure	Homotetramer By similarity.
Subcellular location	PeroxisomeBy similarity.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Catalase		PRO_0000084940
Sites
	Active site	65	1	By similarity
	Active site	138	1	By similarity
	Metal binding	348	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P45739-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 4A5C596506F44961	FASTA	492	56,755
	10 20 30 40 50 60 MDPYKYRSSS AYNAPFWTTN SGAPVYNNNN SLTVGSRGPI LLEDYHLVEK LANFDRERIP 70 80 90 100 110 120 ERVVHARGAS AKGFFEVTHD ITALTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR 130 140 150 160 170 180 GFAVKFYTRE GNFDLVGNNF PVFFIRDGMK FPDMVHSLKP NPKSHIQEDW RIMDFFSHHP 190 200 210 220 230 240 ESLHMFTFLL DDIGVPQDYR HMDGSGVNTY TLINKAGKAY YVKFHWKPTC GVKSLLEEEA 250 260 270 280 290 300 IKIGGANHSH ATQDLYDSIA AGNYPEWKLF IQTIDPDHED RLDFDPLDVT KTWPEDIFPL 310 320 330 340 350 360 QPVGRLVLNK NIDNFFAENE QLAFCPAIIV PGIYYSDDKL LQTRIFSYSD TQRHRLGPNY 370 380 390 400 410 420 LQLPANAPKC AHHNNHYDGF MNFMHRDEEI DYFPSRYDPA RHAEQYPIPP VRLSGKRDKC 430 440 450 460 470 480 VIEKENNFKQ PGERYRSFSP DRQERFINRV VGGLSDPRVT HEVRSIWVSY WSQADKSLGQ 490 KIASRLNVKP NY

References

[1]

"Nucleotide and deduced amino acid sequence of a putative higher molecular weight precursor for catalase in sunflower cotyledons." Kleff S., Trelease R.N., Eising R. Biochim. Biophys. Acta 1224:463-466(1994) [PubMed: 7803505] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Spanners Allzweck. Tissue: Cotyledon.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L28740 mRNA. Translation: AAA69866.1.
PIR	S52079.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Protein family/group databases
PeroxiBase	4087. HaKat01.
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_HELAN

Accession

Primary (citable) accession number: P45739

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)