Reviewed, UniProtKB/Swiss-Prot P45705 (XYNA_BACST)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase A
      Short name=Xylanase A
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:

xynA

Organism

Bacillus stearothermophilus (Geobacillus stearothermophilus)

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 210	191	Endo-1,4-beta-xylanase A		PRO_0000007998
Sites
	Active site	104	1	Nucleophile By similarity
	Active site	197	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P45705-1 [UniParc]. Last modified July 15, 1998. Version 2. Checksum: 3190CF74C34AAB45	FASTA	210	23,221
	10 20 30 40 50 60 MKLKKKMLTL LLTASMSFGL FGATSSAATD YWQYWTDGGG MVNAVNGPGG NYSVTWQNTG 70 80 90 100 110 120 NFVVGKGWTV GSPNRVINYN AGIWEPSGNG YLTLYGWTRN ALIEYYVVDS WGTYRPTGNY 130 140 150 160 170 180 KGTVNSDGGT YDIYTTMRYN APSIDGTQTF QQFWSVRQSK RPTGSNVSIT FSNHVNAWRS 190 200 210 KGMNLGSSWA YQVLATEGYQ SSGRSNVTVW

References

[1]	"Nucleotide sequence analysis of an endo-xylanase gene (xynA) from Bacillus stearothermophilus." Cho S., Choi Y. J. Microbiol. Biotechnol. 5:117-124(1995) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: No. 236.
[2]	Cho S., Choi Y. Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U15985 Genomic DNA. Translation: AAB72117.1.
3D structure databases
SMR	P45705. Positions 24-210.
ModBase	Search...
Protein family/group databases
CAZy	GH11. Glycoside Hydrolase Family 11.
Enzyme and pathway databases
BRENDA	3.2.1.8. 266715.
Family and domain databases
InterPro	IPR008985. ConA-like_lec_gl. IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12_cat. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Gene3D	G3DSA:2.60.120.180. Glyco_hydro_11/12_cat. 1 hit.
Pfam	PF00457. Glyco_hydro_11. 1 hit. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
PROSITE	PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_BACST

Accession

Primary (citable) accession number: P45705

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	July 15, 1998
Last modified:	November 24, 2009
This is version 57 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)