P45704 (XYLA2_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Beta-xylosidase
EC=3.2.1.37

Alternative name(s):
1,4-beta-D-xylan xylohydrolase
Xylan 1,4-beta-xylosidase

Gene names

Name:

xylA

Organism

Geobacillus stearothermophilus (Bacillus stearothermophilus)

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	618 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Sequence similarities	Belongs to the glycosyl hydrolase 52 family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	xylan 1,4-beta-xylosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – ?		Potential
	Chain	? – 618		Beta-xylosidase		PRO_0000012219

Sequences

	Sequence		Length	Mass (Da)
	P45704 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 7D93B25CC8D03B33	FASTA	618	69,627
	10 20 30 40 50 60 MSVEQEVINL GKNIFFNAHH SPMGCSPVFT LGYPGQSGGF DLELGSPPNQ NIYIGLQDDG 70 80 90 100 110 120 QERYRAFPFF GEGLDERDRY TTDESDSGSS ERHSVQQEES GLIIPYNRDE IVRRFGAAID 130 140 150 160 170 180 EWQAGDLTFR LISPFEGVPD PETATEEQLR FALMPAVLAE ITVDNTRGTS TRKAFFGLQN 190 200 210 220 230 240 NDPVSAIRRL EDVTGGRICG IGQGRHTAIA RAIRDYQRRI FYDGIDSQAK GSGKPPVWPW 250 260 270 280 290 300 SGRAVLMDTP AGEKATYRFG LCFYRPVRHN RNRCSYYYSR YFANIEEVAE YALAQFNRKL 310 320 330 340 350 360 EVARQADALV NDAKLSEDQK FIVAHAIRSY YGSTELLEHD GKPLWIVNEG EYRMMNTFDL 370 380 390 400 410 420 LVDQLFYELK MNPWTVKNEL DLYTSRYSYR DTVDFPGDAT EYPGGISFTH DMGVANSFSL 430 440 450 460 470 480 PGYSSYELHA IDDCFSHMTH EQLVNWVLSA TVYVHQTNDR EWLEPQPADS GASLDSMVNR 490 500 510 520 530 540 DHPDPSQRTG MMGLDSSRTM GGRKSPPIQP GRLVGASAEQ HLFAGKSWAA YVAMEKLFRD 550 560 570 580 590 600 NGRKSAAALA GRQPELGAGT ITSHLLPGGI FQPSFRRTMT PRSSLRSRVL SSRYTPDAKK 610 RWIQTADSVH ILRRCPRI

References

[1]	"Sequence analysis of B-xylosidase gene from Bacillus stearothermophilus." Oh H., Choi Y. Korean J. Appl. Microbiol. Biotechnol. 22:134-142(1994) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: No. 236.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U15984 Genomic DNA. Translation: AAA50863.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH52. Glycoside Hydrolase Family 52.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000852. Glyco_hydro_52. [Graphical view]
Pfam	PF03512. Glyco_hydro_52. 1 hit. [Graphical view]
PRINTS	PR00845. GLHYDRLASE52.
ProtoNet	Search...

Entry information

Entry name

XYLA2_GEOSE

Accession

Primary (citable) accession number: P45704

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 31, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program