P45703 (XYN2_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase
Short name=Xylanase
EC=3.2.1.8

Alternative name(s):
1,4-beta-D-xylan xylanohydrolase

Gene names

Name:

xynA

Organism

Geobacillus stearothermophilus (Bacillus stearothermophilus)

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Cytoplasm By similarity.
Induction	By xylan and xylose.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family. Cytoplasmic xylanase subfamily.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Cytoplasm
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	Endo-1,4-beta-xylanase		PRO_0000007969
Sites
	Active site	133	1	Proton donor By similarity
	Active site	240	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	P45703 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 0A2026B23502EB48	FASTA	330	38,473
	10 20 30 40 50 60 MCSSIPSLRE VFANDFRIGA AVNPVTLEAQ QSLLIRHVNS LTAENHMKFE HLQPEEGRFT 70 80 90 100 110 120 FDIAIKSSTS PFSSHGVRGH TLVWHNQTPS WVFQDSQGHF VGRDVLLERM KSHISTVVQR 130 140 150 160 170 180 YKGKVYCWDV INEAVADEGS EWLRSSTWRQ IIGDDFIQQA FLYAHEADPE ALLFYNDYNE 190 200 210 220 230 240 CFPEKREKIY TLVKSLRDKG IPIHGIGMQA HWSLNRPTLD EIRAAIERYA SLGVILHITE 250 260 270 280 290 300 LDISMFEFDD HRKDLAAPTN EMVERQAERY EQIFSLFKEY RDVIQNVTFW GIADDHTWLD 310 320 330 HFPVQGRKNW PLLFDEQHNP KPAFWRVVNI

References

[1]

"Identification and characterization of clustered genes for thermostable xylan-degrading enzymes, beta-xylosidase and xylanase, of Bacillus stearothermophilus 21." Baba T., Shinke R., Nanmori T. Appl. Environ. Microbiol. 60:2252-2258(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 3-7. Strain: No. 21.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D28121 Genomic DNA. Translation: BAA05668.1.
PIR	I39760.
3D structure databases
ProteinModelPortal	P45703.
SMR	P45703. Positions 3-330.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00114.
Family and domain databases
Gene3D	3.20.20.80. 1 hit.
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYN2_GEOSE

Accession

Primary (citable) accession number: P45703

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program