Reviewed, UniProtKB/Swiss-Prot P45703 (XYN2_BACST)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase
      Short name=Xylanase
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase

Gene names

Name:

xynA

Organism

Bacillus stearothermophilus (Geobacillus stearothermophilus)

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Cytoplasm By similarity.
Induction	By xylan and xylose.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family. Cytoplasmic xylanase subfamily.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Cytoplasm
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	Endo-1,4-beta-xylanase		PRO_0000007969
Sites
	Active site	133	1	Proton donor By similarity
	Active site	240	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	P45703-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 0A2026B23502EB48	FASTA	330	38,473
	10 20 30 40 50 60 MCSSIPSLRE VFANDFRIGA AVNPVTLEAQ QSLLIRHVNS LTAENHMKFE HLQPEEGRFT 70 80 90 100 110 120 FDIAIKSSTS PFSSHGVRGH TLVWHNQTPS WVFQDSQGHF VGRDVLLERM KSHISTVVQR 130 140 150 160 170 180 YKGKVYCWDV INEAVADEGS EWLRSSTWRQ IIGDDFIQQA FLYAHEADPE ALLFYNDYNE 190 200 210 220 230 240 CFPEKREKIY TLVKSLRDKG IPIHGIGMQA HWSLNRPTLD EIRAAIERYA SLGVILHITE 250 260 270 280 290 300 LDISMFEFDD HRKDLAAPTN EMVERQAERY EQIFSLFKEY RDVIQNVTFW GIADDHTWLD 310 320 330 HFPVQGRKNW PLLFDEQHNP KPAFWRVVNI

References

[1]

"Identification and characterization of clustered genes for thermostable xylan-degrading enzymes, beta-xylosidase and xylanase, of Bacillus stearothermophilus 21." Baba T., Shinke R., Nanmori T. Appl. Environ. Microbiol. 60:2252-2258(1994) [PubMed: 8074507] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 3-7. Strain: No. 21.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D28121 Genomic DNA. Translation: BAA05668.1.
PIR	I39760.
3D structure databases
HSSP	HSSP built from PDB template 1HIZ based on UniProtKB P40943.
SMR	P45703. Positions 3-330.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 266715.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYN2_BACST

Accession

Primary (citable) accession number: P45703

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)