Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P45699

- GUNK_FUSOX

UniProt

P45699 - GUNK_FUSOX

Protein

Putative endoglucanase type K

Gene
N/A
Organism
Fusarium oxysporum (Fusarium vascular wilt)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei29 – 291NucleophilePROSITE-ProRule annotation
    Active sitei140 – 1401Proton donorBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC
    2. cellulose binding Source: InterPro

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiCBM1. Carbohydrate-Binding Module Family 1.
    GH45. Glycoside Hydrolase Family 45.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative endoglucanase type K (EC:3.2.1.4)
    Alternative name(s):
    Cellulase
    Endo-1,4-beta-glucanase
    OrganismiFusarium oxysporum (Fusarium vascular wilt)
    Taxonomic identifieri5507 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium oxysporum species complex

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 376358Putative endoglucanase type KPRO_0000008024Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP45699.
    SMRiP45699. Positions 20-227.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini335 – 37440CBM1PROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 308290CatalyticAdd
    BLAST
    Regioni309 – 33830LinkerAdd
    BLAST

    Sequence similaritiesi

    Contains 1 CBM1 (fungal-type carbohydrate-binding) domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.40.40.10. 1 hit.
    InterProiIPR014733. Barwin-like_endoglucanase.
    IPR000254. Cellulose-bd_dom_fun.
    IPR000334. Glyco_hydro_45.
    IPR009009. RlpA-like_DPBB.
    [Graphical view]
    PfamiPF00734. CBM_1. 1 hit.
    PF02015. Glyco_hydro_45. 1 hit.
    [Graphical view]
    SMARTiSM00236. fCBD. 1 hit.
    [Graphical view]
    SUPFAMiSSF50685. SSF50685. 1 hit.
    SSF57180. SSF57180. 1 hit.
    PROSITEiPS00562. CBM1_1. 1 hit.
    PS51164. CBM1_2. 1 hit.
    PS01140. GLYCOSYL_HYDROL_F45. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P45699-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSYTLLALA GPLAVSAASG SGHSTRYWDC CKPSCSWSGK AAVNAPALTC    50
    DKNDNPISNT NAVNGCEGGG SAYACTNYSP WAVNDELAYG FAATKISGGS 100
    EASWCCACYA LTFTTGPVKG KKMIVQSTNT GGDLGDNHFD LMMPGGGVGI 150
    FDGCTSEFGK ALGGAQYGGI SSRSECDSYP ELLKDGCHWR FDWFENADNP 200
    DFTFEQVQCP KALLDISGCK RDDDSSFPAF KGDTSASKPQ PSSSAKKTTS 250
    AAAAAQPQKT KDSAPVVQKS STKPAAQPEP TKPADKPQTD KPVATKPAAT 300
    KPAQPVNKPK TTQKVRGTKT RGSCPAKTDA TAKASVVPAY YQCGGSKSAY 350
    PNGNLACATG SKCVKQNEYY SQCVPN 376
    Length:376
    Mass (Da):39,236
    Last modified:November 1, 1995 - v1
    Checksum:iB430A5F962B9F882
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L29381 mRNA. Translation: AAA65589.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L29381 mRNA. Translation: AAA65589.1 .

    3D structure databases

    ProteinModelPortali P45699.
    SMRi P45699. Positions 20-227.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM1. Carbohydrate-Binding Module Family 1.
    GH45. Glycoside Hydrolase Family 45.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.40.40.10. 1 hit.
    InterProi IPR014733. Barwin-like_endoglucanase.
    IPR000254. Cellulose-bd_dom_fun.
    IPR000334. Glyco_hydro_45.
    IPR009009. RlpA-like_DPBB.
    [Graphical view ]
    Pfami PF00734. CBM_1. 1 hit.
    PF02015. Glyco_hydro_45. 1 hit.
    [Graphical view ]
    SMARTi SM00236. fCBD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50685. SSF50685. 1 hit.
    SSF57180. SSF57180. 1 hit.
    PROSITEi PS00562. CBM1_1. 1 hit.
    PS51164. CBM1_2. 1 hit.
    PS01140. GLYCOSYL_HYDROL_F45. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The use of conserved cellulase family-specific sequences to clone cellulase homologue cDNAs from Fusarium oxysporum."
      Sheppard P.O., Grant F.J., Oort P.J., Sprecher C.A., Foster D.C., Hagen F.S., Upshall A., McKnight G.L., O'Hara P.J.
      Gene 150:163-167(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiGUNK_FUSOX
    AccessioniPrimary (citable) accession number: P45699
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3