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P45681

- SURE_HAEIN

UniProt

P45681 - SURE_HAEIN

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Protein
5'-nucleotidase SurE
Gene
surE, HI_0702
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

Binds 1 divalent metal cation per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi8 – 81Divalent metal cation By similarity
Metal bindingi9 – 91Divalent metal cation By similarity
Metal bindingi39 – 391Divalent metal cation By similarity
Metal bindingi91 – 911Divalent metal cation By similarity

GO - Molecular functioni

  1. 5'-nucleotidase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-HAMAP
  3. nucleotide binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    5'-nucleotidase SurE (EC:3.1.3.5)
    Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase
    Gene namesi
    Name:surE
    Ordered Locus Names:HI_0702
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cytoplasm Reviewed prediction UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2492495'-nucleotidase SurEUniRule annotation
    PRO_0000111814Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0702.

    Structurei

    3D structure databases

    ProteinModelPortaliP45681.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SurE nucleotidase family.

    Phylogenomic databases

    eggNOGiCOG0496.
    KOiK03787.
    OMAiVCDLIPK.
    OrthoDBiEOG68WR45.
    PhylomeDBiP45681.

    Family and domain databases

    Gene3Di3.40.1210.10. 1 hit.
    HAMAPiMF_00060. SurE.
    InterProiIPR002828. SurE-like_Pase/nucleotidase.
    [Graphical view]
    PfamiPF01975. SurE. 1 hit.
    [Graphical view]
    SUPFAMiSSF64167. SSF64167. 1 hit.
    TIGRFAMsiTIGR00087. surE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P45681-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRILVSNDDG FHAEGIQVLA TELRKIAEVI IVAPDRNRSA ASSSLTLVEP    50
    LRPRHLDNGD YCVNGTPADC VHLALNGFLS GQVDLVVSGI NAGCNMGDDT 100
    IYSGTLAAAL EGRHLGLPAI AVSLDGRQHY ETAARVVCDL IPKLQHQLLN 150
    PREIININVP DLPFEELKGY KVCRLGYRSS SVEVIKQRDP RDETIYWIGP 200
    SALPEDESEG TDFYAVKNGY VSITPIQADL TAYHSLLSLQ NWLDQEFTK 249
    Length:249
    Mass (Da):27,340
    Last modified:November 1, 1995 - v1
    Checksum:iD10F280C95266757
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22361.1.
    PIRiT09407.
    RefSeqiNP_438861.1. NC_000907.1.
    WP_005694588.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22361; AAC22361; HI_0702.
    GeneIDi949728.
    KEGGihin:HI0702.
    PATRICi20190023. VBIHaeInf48452_0733.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22361.1 .
    PIRi T09407.
    RefSeqi NP_438861.1. NC_000907.1.
    WP_005694588.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P45681.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0702.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22361 ; AAC22361 ; HI_0702 .
    GeneIDi 949728.
    KEGGi hin:HI0702.
    PATRICi 20190023. VBIHaeInf48452_0733.

    Phylogenomic databases

    eggNOGi COG0496.
    KOi K03787.
    OMAi VCDLIPK.
    OrthoDBi EOG68WR45.
    PhylomeDBi P45681.

    Family and domain databases

    Gene3Di 3.40.1210.10. 1 hit.
    HAMAPi MF_00060. SurE.
    InterProi IPR002828. SurE-like_Pase/nucleotidase.
    [Graphical view ]
    Pfami PF01975. SurE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF64167. SSF64167. 1 hit.
    TIGRFAMsi TIGR00087. surE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiSURE_HAEIN
    AccessioniPrimary (citable) accession number: P45681
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: September 3, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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