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P45681 (SURE_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
5'-nucleotidase SurE

EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:HI_0702
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP-Rule MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP-Rule MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00060.

Sequence similarities

Belongs to the SurE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function5'-nucleotidase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2492495'-nucleotidase SurE HAMAP-Rule MF_00060
PRO_0000111814

Sites

Metal binding81Divalent metal cation By similarity
Metal binding91Divalent metal cation By similarity
Metal binding391Divalent metal cation By similarity
Metal binding911Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
P45681 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: D10F280C95266757

FASTA24927,340
        10         20         30         40         50         60 
MRILVSNDDG FHAEGIQVLA TELRKIAEVI IVAPDRNRSA ASSSLTLVEP LRPRHLDNGD 

        70         80         90        100        110        120 
YCVNGTPADC VHLALNGFLS GQVDLVVSGI NAGCNMGDDT IYSGTLAAAL EGRHLGLPAI 

       130        140        150        160        170        180 
AVSLDGRQHY ETAARVVCDL IPKLQHQLLN PREIININVP DLPFEELKGY KVCRLGYRSS 

       190        200        210        220        230        240 
SVEVIKQRDP RDETIYWIGP SALPEDESEG TDFYAVKNGY VSITPIQADL TAYHSLLSLQ 


NWLDQEFTK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22361.1.
PIRT09407.
RefSeqNP_438861.1. NC_000907.1.

3D structure databases

ProteinModelPortalP45681.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0702.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22361; AAC22361; HI_0702.
GeneID949728.
KEGGhin:HI0702.
PATRIC20190023. VBIHaeInf48452_0733.

Phylogenomic databases

eggNOGCOG0496.
KOK03787.
OMAVCDLIPK.
OrthoDBEOG68WR45.
PhylomeDBP45681.

Family and domain databases

Gene3D3.40.1210.10. 1 hit.
HAMAPMF_00060. SurE.
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SSF64167. 1 hit.
TIGRFAMsTIGR00087. surE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_HAEIN
AccessionPrimary (citable) accession number: P45681
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names