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Protein

Larval/pupal rigid cuticle protein 66

Gene

CP66

Organism
Hyalophora cecropia (Cecropia moth)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Component of the rigid cuticle of the larva and pupa of Hyalophora cecropia.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Larval/pupal rigid cuticle protein 66
Alternative name(s):
HCCP66
Gene namesi
Name:CP66
OrganismiHyalophora cecropia (Cecropia moth)
Taxonomic identifieri7123 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaBombycoideaSaturniidaeSaturniinaeAttaciniHyalophora

Subcellular locationi

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 171 PublicationAdd BLAST17
ChainiPRO_000000638618 – 129Larval/pupal rigid cuticle protein 66Add BLAST112

Expressioni

Tissue specificityi

Expressed in larval wing disc, forewing disc, diapausing wing, adult wing, and in very low amounts in fat body and testes.

Developmental stagei

Mostly present in young pupal wings and larval tubercles. Faintly present in younger than 24 hours old pupal forewing and hindwing. Weakly detected in hindwing and tubercles.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 90Chitin-binding type R&RPROSITE-ProRule annotationAdd BLAST73

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR031311. CHIT_BIND_RR_consensus.
IPR000618. Insect_cuticle.
PfamiView protein in Pfam
PF00379. Chitin_bind_4. 1 hit.
PROSITEiView protein in PROSITE
PS00233. CHIT_BIND_RR_1. 1 hit.
PS51155. CHIT_BIND_RR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P45590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVKFVACFV FVAVASASDF SSFSYGVADP STGDFKSQIE SRLGDNVQGQ
60 70 80 90 100
YSLLESDGTQ RTVDYAAGSE GFNAVVRKDP ALIAAAPYIT APYGYAVPYA
110 120
YTSPYGISNL ANYRALKFAS ALPYSRVFF
Length:129
Mass (Da):13,878
Last modified:November 1, 1995 - v1
Checksum:i8914FEC3F940DCC6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti105Y → F AA sequence (PubMed:8025561).Curated1
Sequence conflicti108S → F AA sequence (PubMed:8025561).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13971 Genomic DNA. Translation: AAC37204.1.

Similar proteinsi

Entry informationi

Entry nameiCU66_HYACE
AccessioniPrimary (citable) accession number: P45590
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 12, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing