P45588 (CU76_LOCMI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Cuticle protein 76 Alternative name(s): LM-ACP 76 Short name=LM-76
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular_function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Cuticle protein 76		PRO_0000196113
Regions
	Repeat	7 – 10	4	1
	Repeat	68 – 71	4	2
	Repeat	75 – 78	4	3
	Repeat	93 – 95	3	4
	Repeat	105 – 108	4	5
	Repeat	121 – 124	4	6

Sequences

	Sequence		Length	Mass (Da)
	P45588 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 061D6B308EAABC95	FASTA	139	13,695
	10 20 30 40 50 60 GYLGGYAAPA LAYGAAAVAP AAITSQQSNI LRSYGNLGQV STYSKTVDTP YSSVSKADIR 70 80 90 100 110 120 VTNNAVYAAP AAYAAAPVAY AAPALGYART ALAAPALGYA RAAYAAPAVA AGGLLGVAYS 130 AAPAVAHLTY SGLHAAYAY

References

[1]	"Primary structure of a 14 kDa basic structural protein (Lm-76) from the cuticle of the migratory locust, Locusta migratoria." Andersen J.S., Andersen S.O., Hoejrup P., Roepstorff P. Insect Biochem. Mol. Biol. 23:391-402(1993) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
PIR	A56585.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR022727. Cuticle_C1. [Graphical view]
Pfam	PF11018. Cuticle_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CU76_LOCMI

Accession

Primary (citable) accession number: P45588

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)