Reviewed, UniProtKB/Swiss-Prot P45585 (CU65_LOCMI)

Names and origin

Protein names	Recommended name:     Cuticle protein 65 Alternative name(s):     LM-ACP 65       Short name=LM-65
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Mass spectrometry	Molecular weight is 13319.9 Da from positions 1 - 145. Determined by ESI. Ref.1

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	Cuticle protein 65		PRO_0000196109
Regions
	Repeat	27 – 30	4	1
	Repeat	33 – 37	5	2
	Repeat	39 – 42	4	3
	Repeat	86 – 89	4	4
	Repeat	92 – 95	4	5
	Repeat	98 – 101	4	6
	Repeat	123 – 126	4	7

Sequences

	Sequence		Length	Mass (Da)
	P45585-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 6677E36A4D52148A	FASTA	145	13,318
	10 20 30 40 50 60 GLLGLGYGGY GGYGGYGGYG HGLALAAAPA AIAAPAVVAA PAIAHAPAVA VAPAVAHAPA 70 80 90 100 110 120 AVSTVSQVSY GTTHYAPAVA KVAAVAAPVA VAAPAIAAAP AVGLGYGHGL GYGHGVGLGY 130 140 AAAAPALSLG YGGYGHGLSL GYGHH

References

[1]	"Primary structure of proteins from the wing cuticle of the migratory locust, Locusta migratoria." Krogh T.N., Skou L., Roepstorff P., Andersen S.O., Hoejrup P. Insect Biochem. Mol. Biol. 25:319-329(1995) [PubMed: 7773253] [Abstract] Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY. Tissue: Wing.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CU65_LOCMI

Accession

Primary (citable) accession number: P45585

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)