Reviewed, UniProtKB/Swiss-Prot P45584 (CU63_LOCMI)

Names and origin

Protein names	Recommended name:     Cuticle protein 63 Alternative name(s):     LM-ACP 63       Short name(s)=LM-63
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	157 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Mass spectrometry	Molecular weight is 14492.2 Da from positions 1 - 157. Determined by ESI. Ref.1

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Molecular function	Structural protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 157	157	Cuticle protein 63
Regions
	Repeat	27 – 30	4	1
	Repeat	33 – 37	5	2
	Repeat	39 – 42	4	3
	Repeat	84 – 87	4	4
	Repeat	90 – 93	4	5
	Repeat	96 – 99	4	6
	Repeat	102 – 105	4	7
	Repeat	135 – 138	4	8

Sequences

	Sequence		Length	Mass (Da)
	P45584-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: F231C38315384F1C	FASTA	157	14,492
	10 20 30 40 50 60 GLLGLGYGGY SGYGGYGGYG HGLALAAAPA AIAAPAVVAA PAIAHAPAVA VAPAVAHAPA 70 80 90 100 110 120 AVSTVSQVSY GTTHYAPAVA KVAAAPVAVA APAIAAAPAI AAAPAVGLGY GQGLSLGYGH 130 140 150 GLGYGHGLSL GYAAAAPALS LGYGGYGHGL SLGYGHH

References

[1]	"Primary structure of proteins from the wing cuticle of the migratory locust, Locusta migratoria." Krogh T.N., Skou L., Roepstorff P., Andersen S.O., Hoejrup P. Insect Biochem. Mol. Biol. 25:319-329(1995) [PubMed: 7773253] [Abstract] Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY. Tissue: Wing.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProDom	P45584. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

CU63_LOCMI

Accession

Primary (citable) accession number: P45584

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	July 22, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)