Reviewed, UniProtKB/Swiss-Prot P45583 (CU19_LOCMI)

Names and origin

Protein names	Recommended name:     Cuticle protein 19 Alternative name(s):     LM-ACP 19       Short name=LM-19
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	157 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Sequence similarities	Contains 1 chitin-binding type R&R domain.
Mass spectrometry	Molecular weight is 16127.7 Da from positions 1 - 157. Determined by ESI. Ref.1

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 157	157	Cuticle protein 19		PRO_0000196100
Regions
	Repeat	11 – 14	4	1
	Repeat	18 – 21	4	2
	Repeat	24 – 27	4	3
	Repeat	29 – 32	4	4
	Repeat	39 – 42	4	5
	Repeat	47 – 50	4	6
	Domain	56 – 127	72	Chitin-binding type R&R
	Repeat	141 – 144	4	7

Sequences

	Sequence		Length	Mass (Da)
	P45583-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 43D58E0ABA2CB470	FASTA	157	16,129
	10 20 30 40 50 60 GYLGGYAGYA AAPAAYAAAP AAYAAPAYAA PAVVKTAYAA PAIVKAAAPA VDYYSYPKYA 70 80 90 100 110 120 FEYGVNDPHT GDVKRQWEER DGDVVRGEYS LLEPDGTTRT VTYTADAHNG FNAVVHRSGP 130 140 150 SAHPAPAPAV AVPAVAKYVA AAPAVVKSVG YGGYGYH

References

[1]	"Primary structure of proteins from the wing cuticle of the migratory locust, Locusta migratoria." Krogh T.N., Skou L., Roepstorff P., Andersen S.O., Hoejrup P. Insect Biochem. Mol. Biol. 25:319-329(1995) [PubMed: 7773253] [Abstract] Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY. Tissue: Wing.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR000618. Insect_cuticle. [Graphical view]
Pfam	PF00379. Chitin_bind_4. 1 hit. [Graphical view]
PRINTS	PR00947. CUTICLE.
PROSITE	PS00233. CHIT_BIND_RR_1. 1 hit. PS51155. CHIT_BIND_RR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CU19_LOCMI

Accession

Primary (citable) accession number: P45583

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)