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P45577 (PROQ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ProP effector
Gene names
Name:proQ
Synonyms:yebJ, yobE, yoeC
Ordered Locus Names:b1831, JW5300
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Not exactly known; may be a structural element that influences the osmotic activation of ProP at a post-translational level. HAMAP-Rule MF_00749

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00749.

Sequence similarities

Belongs to the ProQ family.

Sequence caution

The sequence BAA20566.1 differs from that shown. Reason: Erroneous initiation.

The sequence described in Ref.5 differs from that shown. Reason: Frameshift at position 151.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

evgAP0ACZ43EBI-8767901,EBI-548694

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 232232ProP effector HAMAP-Rule MF_00749
PRO_0000214614

Sequences

Sequence LengthMass (Da)Tools
P45577 [UniParc].

Last modified July 15, 1999. Version 2.
Checksum: 042BEAA345A3C739

FASTA23225,893
        10         20         30         40         50         60 
MENQPKLNSS KEVIAFLAER FPHCFSAEGE ARPLKIGIFQ DLVDRVAGEM NLSKTQLRSA 

        70         80         90        100        110        120 
LRLYTSSWRY LYGVKPGATR VDLDGNPCGE LDEQHVEHAR KQLEEAKARV QAQRAEQQAK 

       130        140        150        160        170        180 
KREAAATAGE KEDAPRRERK PRPTTPRRKE GAERKPRAQK PVEKAPKTVK APREEQHTPV 

       190        200        210        220        230 
SDISALTVGQ ALKVKAGQNA MDATVLEITK DGVRVQLNSG MSLIVRAEHL VF 

« Hide

References

« Hide 'large scale' references
[1]"Protein ProQ influences osmotic activation of compatible solute transporter ProP in Escherichia coli K-12."
Kunte H.J., Crane R.A., Culham D.E., Richmond D., Wood J.M.
J. Bacteriol. 181:1537-1543(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL CHARACTERIZATION.
Strain: K12.
[2]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Cloning, mapping, and characterization of the Escherichia coli prc gene, which is involved in C-terminal processing of penicillin-binding protein 3."
Hara H., Yamamoto Y., Higashitani A., Suzuki H., Nishimura Y.
J. Bacteriol. 173:4799-4813(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 146-232.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]"Detection of new genes in a bacterial genome using Markov models for three gene classes."
Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A.
Nucleic Acids Res. 23:3554-3562(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L48409 Genomic DNA. Translation: AAD41527.1.
U00096 Genomic DNA. Translation: AAC74901.2.
AP009048 Genomic DNA. Translation: BAA15639.2.
D00674 Genomic DNA. Translation: BAA20566.1. Different initiation.
PIRG64944.
RefSeqYP_026161.1. NC_000913.3.
YP_490093.1. NC_007779.1.

3D structure databases

DisProtDP00377.
ProteinModelPortalP45577.
SMRP45577. Positions 7-111.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-10572N.
IntActP45577. 43 interactions.
STRING511145.b1831.

Proteomic databases

PaxDbP45577.
PRIDEP45577.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74901; AAC74901; b1831.
BAA15639; BAA15639; BAA15639.
GeneID12931702.
948950.
KEGGecj:Y75_p1807.
eco:b1831.
PATRIC32118983. VBIEscCol129921_1909.

Organism-specific databases

EchoBASEEB2707.
EcoGeneEG12866. proQ.

Phylogenomic databases

eggNOGCOG3109.
HOGENOMHOG000290843.
KOK03607.
OMAGELEQQH.
OrthoDBEOG6T1WWT.

Enzyme and pathway databases

BioCycEcoCyc:EG12866-MONOMER.
ECOL316407:JW5300-MONOMER.

Gene expression databases

GenevestigatorP45577.

Family and domain databases

Gene3D1.10.1710.10. 1 hit.
HAMAPMF_00749. ProQ.
InterProIPR016103. ProQ/FinO.
IPR023529. Transptr_ProQ.
[Graphical view]
PfamPF04352. ProQ. 1 hit.
[Graphical view]
SMARTSM00945. ProQ. 1 hit.
[Graphical view]
SUPFAMSSF48657. SSF48657. 1 hit.
ProtoNetSearch...

Other

PROP45577.

Entry information

Entry namePROQ_ECOLI
AccessionPrimary (citable) accession number: P45577
Secondary accession number(s): P56606
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 15, 1999
Last modified: June 11, 2014
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene