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Protein

Uncharacterized protein YhfW

Gene

yhfW

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Mn2+CuratedNote: Binds 1 or 2 manganese ions.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi10 – 101ManganeseBy similarity
Metal bindingi302 – 3021ManganeseBy similarity
Metal bindingi338 – 3381ManganeseBy similarity
Metal bindingi339 – 3391ManganeseBy similarity
Metal bindingi350 – 3501ManganeseBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7732-MONOMER.
ECOL316407:JW3343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YhfW
Gene namesi
Name:yhfW
Ordered Locus Names:b3380, JW3343
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12918. yhfW.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Uncharacterized protein YhfWPRO_0000199866Add
BLAST

Proteomic databases

PaxDbiP45549.
PRIDEiP45549.

Interactioni

Protein-protein interaction databases

BioGridi4262082. 69 interactions.
IntActiP45549. 2 interactions.
STRINGi511145.b3380.

Structurei

3D structure databases

ProteinModelPortaliP45549.
SMRiP45549. Positions 3-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphopentomutase family.Curated

Phylogenomic databases

eggNOGiENOG4105CZG. Bacteria.
COG1015. LUCA.
HOGENOMiHOG000008160.
InParanoidiP45549.
OMAiHQEIMGT.
OrthoDBiEOG6SZ1DF.
PhylomeDBiP45549.

Family and domain databases

Gene3Di3.40.720.10. 2 hits.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR010045. DeoB.
IPR006124. Metalloenzyme.
[Graphical view]
PfamiPF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001491. Ppentomutase. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.

Sequencei

Sequence statusi: Complete.

P45549-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARFVVLVID SFGVGAMKDV TLVRPQDAGA NTCGHILSQL PHLQLPTLET
60 70 80 90 100
LGLINALGYA PGDMQPSDSA TWGVAELQHE GGDTFMGHQE ILGTRPLPPL
110 120 130 140 150
RMPFRDVIDR VEQALVSAGW QVERRGDDLQ FLWVNQAVAI GDNLEADLGQ
160 170 180 190 200
VYNITANLSV ISFDDAIKIG RIVREQVQVG RVITFGGLLT DSQRILDAAE
210 220 230 240 250
SKEGRFIGIN APRSGAYDNG FQVVHMGYGV DEKVQVPQKL YEAGVPTVLV
260 270 280 290 300
GKVADIVNNP YGVSWQNLVD SQRIMDITLN EFNTHPTAFI CTNIQETDLA
310 320 330 340 350
GHAEDVARYA ERLQVVDRNL ARLVEAMQPD DCLVVMADHG NDPTIGHSHH
360 370 380 390 400
TREVVPVLVY QQGMIATQLG VRTTLSDVGA TVCEFFRAPP PQNGRSFLSS

LRFAGDTL
Length:408
Mass (Da):44,560
Last modified:November 1, 1995 - v1
Checksum:i147CBB78F99AF8C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58177.1.
U00096 Genomic DNA. Translation: AAC76405.1.
AP009048 Genomic DNA. Translation: BAE77911.1.
PIRiG65132.
RefSeqiNP_417839.1. NC_000913.3.
WP_000090644.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76405; AAC76405; b3380.
BAE77911; BAE77911; BAE77911.
GeneIDi947890.
KEGGiecj:JW3343.
eco:b3380.
PATRICi32122192. VBIEscCol129921_3473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58177.1.
U00096 Genomic DNA. Translation: AAC76405.1.
AP009048 Genomic DNA. Translation: BAE77911.1.
PIRiG65132.
RefSeqiNP_417839.1. NC_000913.3.
WP_000090644.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP45549.
SMRiP45549. Positions 3-401.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262082. 69 interactions.
IntActiP45549. 2 interactions.
STRINGi511145.b3380.

Proteomic databases

PaxDbiP45549.
PRIDEiP45549.

Protocols and materials databases

DNASUi947890.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76405; AAC76405; b3380.
BAE77911; BAE77911; BAE77911.
GeneIDi947890.
KEGGiecj:JW3343.
eco:b3380.
PATRICi32122192. VBIEscCol129921_3473.

Organism-specific databases

EchoBASEiEB2754.
EcoGeneiEG12918. yhfW.

Phylogenomic databases

eggNOGiENOG4105CZG. Bacteria.
COG1015. LUCA.
HOGENOMiHOG000008160.
InParanoidiP45549.
OMAiHQEIMGT.
OrthoDBiEOG6SZ1DF.
PhylomeDBiP45549.

Enzyme and pathway databases

BioCyciEcoCyc:G7732-MONOMER.
ECOL316407:JW3343-MONOMER.

Miscellaneous databases

PROiP45549.

Family and domain databases

Gene3Di3.40.720.10. 2 hits.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR010045. DeoB.
IPR006124. Metalloenzyme.
[Graphical view]
PfamiPF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001491. Ppentomutase. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYHFW_ECOLI
AccessioniPrimary (citable) accession number: P45549
Secondary accession number(s): Q2M745
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 6, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.