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Protein

Protein FrlC

Gene

frlC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Not clear, may be involved in an isomerization step.

Pathwayi: fructoselysine degradation

This protein is involved in the pathway fructoselysine degradation, which is part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the pathway fructoselysine degradation and in Carbohydrate metabolism.

GO - Molecular functioni

  • identical protein binding Source: EcoCyc
  • racemase and epimerase activity, acting on carbohydrates and derivatives Source: EcoCyc

GO - Biological processi

  • amino sugar catabolic process Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7724-MONOMER.
ECOL316407:JW5699-MONOMER.
MetaCyc:G7724-MONOMER.
UniPathwayiUPA00784.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FrlC
Gene namesi
Name:frlC
Synonyms:yhfO, yhfP
Ordered Locus Names:b4474, JW5699
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12910. frlC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000873381 – 276Protein FrlCAdd BLAST276

Proteomic databases

PaxDbiP45541.
PRIDEiP45541.

Interactioni

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

IntActiP45541. 1 interactor.
STRINGi511145.b4474.

Structurei

3D structure databases

ProteinModelPortaliP45541.
SMRiP45541.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4107Y0V. Bacteria.
COG1082. LUCA.
HOGENOMiHOG000005027.
InParanoidiP45541.
KOiK10709.
OMAiTRHIHIE.
PhylomeDBiP45541.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.

Sequencei

Sequence statusi: Complete.

P45541-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTGMFTCGH QRLPIEHAFR DASELGYDGI EIWGGRPHAF APDLKAGGIK
60 70 80 90 100
QIKALAQTYQ MPIIGYTPET NGYPYNMMLG DEHMRRESLD MIKLAMDMAK
110 120 130 140 150
EMNAGYTLIS AAHAGYLTPP NVIWGRLAEN LSELCEYAEN IGMDLILEPL
160 170 180 190 200
TPYESNVVCN ANDVLHALAL VPSPRLFSMV DICAPYVQAE PVMSYFDKLG
210 220 230 240 250
DKLRHLHIVD SDGASDTHYI PGEGKMPLRE LMRDIIERGY EGYCTVELVT
260 270
MYMNEPRLYA RQALERFRAL LPEDER
Length:276
Mass (Da):31,169
Last modified:October 24, 2003 - v3
Checksum:i6C263FC8C4F945EA
GO

Sequence cautioni

The sequence AAA58169 differs from that shown. Reason: Frameshift at position 112.Curated
The sequence AAA58170 differs from that shown. Reason: Frameshift at position 112.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58169.1. Frameshift.
U18997 Genomic DNA. Translation: AAA58170.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48177.1.
AP009048 Genomic DNA. Translation: BAE77918.1.
PIRiH65131.
RefSeqiWP_000847837.1. NZ_LN832404.1.
YP_026213.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48177; AAT48177; b4474.
BAE77918; BAE77918; BAE77918.
GeneIDi2847758.
KEGGiecj:JW5699.
eco:b4474.
PATRICi32122178. VBIEscCol129921_3466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA58169.1. Frameshift.
U18997 Genomic DNA. Translation: AAA58170.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48177.1.
AP009048 Genomic DNA. Translation: BAE77918.1.
PIRiH65131.
RefSeqiWP_000847837.1. NZ_LN832404.1.
YP_026213.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP45541.
SMRiP45541.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP45541. 1 interactor.
STRINGi511145.b4474.

Proteomic databases

PaxDbiP45541.
PRIDEiP45541.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48177; AAT48177; b4474.
BAE77918; BAE77918; BAE77918.
GeneIDi2847758.
KEGGiecj:JW5699.
eco:b4474.
PATRICi32122178. VBIEscCol129921_3466.

Organism-specific databases

EchoBASEiEB2747.
EcoGeneiEG12910. frlC.

Phylogenomic databases

eggNOGiENOG4107Y0V. Bacteria.
COG1082. LUCA.
HOGENOMiHOG000005027.
InParanoidiP45541.
KOiK10709.
OMAiTRHIHIE.
PhylomeDBiP45541.

Enzyme and pathway databases

UniPathwayiUPA00784.
BioCyciEcoCyc:G7724-MONOMER.
ECOL316407:JW5699-MONOMER.
MetaCyc:G7724-MONOMER.

Miscellaneous databases

PROiP45541.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFRLC_ECOLI
AccessioniPrimary (citable) accession number: P45541
Secondary accession number(s): P45542, Q2M738
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 24, 2003
Last modified: November 2, 2016
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.